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Illumina

Illumina

Illumina is a biotechnology company founded in 1998 located in San Diego, California, developing and selling instruments, reagents, and services for DNA sequencing applications.

Illumina is headquartered in San Diego, California and was founded in 1998 by David Walt, John Stuelpnagel, Anthony Czarnik, Lawrence Bock, and Marck Chee, to develop, manufacture, and commercialize DNA sequencing technologies. The company is a global provider of DNA sequencing instruments, reagents, and services, that serve biotechnology markets such as DNA sequencing, genotyping, gene expression analysis, and proteomics. Illumina's customers are pharmaceutical companies, educational institutions, research scientists, biotechnology companies, and clinical research organizations.

Illumina has two distinct business units. The first focuses on life science related products and services such as DNA sequencing, bead arrays, vera-codes, and PCR technologies. The second unit focuses on the development and sale of technologies related to medical diagnostics.

According to Wired magazine, in 2016 Illumina's DNA sequencing machines perform 90% of global DNA sequencing. The director of global public relations for Illumina in 2016 told reporters, "We are at a tipping point in genomics, where a broad community of scientists and researchers continue to translate the potential of the genome from science to discoveries and applications" and believes DNA sequencing technologies made by Illumina will continue to be in high demand around the world well into the future.

DNA sequencing machines made by Illumina are based off DNA sequencing technologies developed by Solexa in the early to mid 2000's. Illumina acquired Solexa in 2007 for $600 million after Solexa successfully built a next generation sequencing machine that could sequence 1 gigabase (Gb) of data in a single run of the machine.

Illumina Accelerator

Illumina Accelerator is the investment arm of Illumina funding early stage genomics companies. They offer early stage companies financial support, mentorship and access to genomic technologies such as sequencing systems, reagents, and lab space.

Accelerator program

The Illumina Accelerator runs 2 six month funding cycles each year consisting of up to 5 companies per cycle with access to up to $100,000 in convertible notes from seed investors and a $20,000 unsecured line of credit. Chosen companies agree to give Illumina Accelerator 8% of common stock for participating in their accelerator program.

During each six month funding cycle selected companies are actively coached by mentors at the Illumina Accelerator to develop a custom curriculum for company building, business strategy, technology development, and pitch development. Credits are given to each company for access to Illumina sequencing technologies, and companies can hire scientists at illumina to help with experimental design. At the end of each funding cycle companies meet with venture capitalists affiliated with the Illumina Accelerator to pitch their business ideas and technologies.

Companies also have the opportunity to receive funding from a $40 million dollar pool of funding from the Illumina Accelerator Boost Capital fund. Illumina Accelerator Boost Capital has a deal with Viking Global Investors to match funding dollar-for-dollar for startups managing to raise in between $1 million and $5 million in funding.

Grant Competition

Illumina Accelerator's grant competition encourages entrepreneurs to create companies using next generation sequencing technologies. Grant winners are able to spend one week running sequencing experiments for proof-of-concept at Illumina Accelerator. When the grant is awarded it needs to be used within 6-months. The grant also gives entrepreneurs one business coaching session, and two sequencing experiment design meetings with a senior scientist at Illumina.

Partnerships
Helix

On August 17, 2017 Illumina Accelerator announced they will collaborating with a personal genomics company called Helix. The partnership seeks to help entrepreneurs develop DNA-driven products and services. Startups accepted into Illumina Accelerator's accelerator program will gain access to Helix's expertise and sequencing platform. The co-founder and senior vice president of Helix, Justin Kao, had the following to say about the partnership "We are proud to collaborate with Illumina Accelerator to stimulate innovation in personal genomics by helping selected startups harness their creativity and build best-in-class DNA-powered products for everyday use".

Investment portfolio

Timeline

April 22, 2021
Illumina and Kartos Therapeutics announce new oncology partnership to develop an NGS-based TP53 companion diagnostic.
May 2018
Illumina acquires Edico Genome for an undisclosed amount.
1998
Illumina was founded by Amanda Cashin.

Funding rounds

People

Name
Role
LinkedIn

Amanda Cashin

Head of Illumina Accelerator & Co-Founder

Anthony Czarnik

Co-Founder

Charles Dadswell

Senior Vice President & General Counsel

Dave Grimm

Digital Experience Director

David Walt

Co-Founder, Board Director

Francis deSouza

President

Francis deSouza

Chief Executive Officer

Jay Flatley

President, Chief Executive Officer

John Liebig

Vice President of Customer Solutions

John Stuelpnagel

Co-Founder, Senior Vice President

Larry Bock

Co-Founder

Licen Xu

Vice President Product Management, Strategic Marketing

Marc Stapey

Executive Vice President, Chief Administrative Officer, & Chief Financial Officer

Mark Chee

Co-Founder

Mostafa Ronaghi

Chief Technical Officer & Co-Founder

Mostafa Ronaghi

Senior Vice President, Chief Technology Officer

Nick Naclerio

Senior Vice President Corporate Development and General Manager Enterprise Informatics

Omead Ostadan

Executive Vice President. Operations, Products & Strategy

Ray Alley

Senior System Engineer

Richard Klausner

Senior VIce President, Chief Medical Officer

Richard Klausner

Chief Medical Officer & Interim General Manager

Sanjay Chikarmane

Senior Vice President & General Manager of Enterprise Informatics

Seems Rego

Associate Director, Global Clinical Operations

Simon Valentine

Global Head of Sales, Enterprise Informatics

Tristan Orpin

Senior Vice President, Chief Commercial Officer

Further reading

Title
Author
Link
Type
Date

$40 million genomics accelerator introduced by Helix and Illumina

Richard Harris

News article

Illumina Accelerator explores genomic innovation in Ontario - Ontario Genomics

Ontario Genomics

News article

Illumina Might Be Overlooking Its Top Competitor; Here's Why Investors Shouldn't

Maxx Chatsko

Web article

Illumina, the Google of Genetic Testing, Has Plans for World Domination

Sarah Zhang

Web article

The genomics-focused Illumina Accelerator backs five new companies

Jonathan Shieber

News article

Documentaries, videos and podcasts

Title
Date
Link

Companies

Company
CEO
Location
Products/Services

News

Title
Author
Date
Publisher
Description
Andrea Park
September 7, 2021
FierceBiotech
The tests will be used to identify ovarian cancer patients with genetic mutations that have been found to respond well to PARP inhibitors, a type of targeted cancer drug, reducing the need for intensive chemotherapy and radiation exposure.
Conor Hale
August 19, 2021
FierceBiotech
Despite looming antitrust investigations on both sides of the Atlantic, Illumina has pushed forward with its $8 billion deal to acquire Grail, maker of a newly launched blood test to detect dozens of different cancers.
Alexandra Ames
August 17, 2021
TechCrunch
Solving the twin challenges of human and planetary health is the greatest task of our generation, and it also presents the greatest entrepreneurial opportunity in history which is why we've partnered with Mayfield to bring you an engineering biology track to Disrupt 2021 this September 21-23. Haven't secured your spot yet? Grab your ticket now [...]
Conor Hale
August 6, 2021
FierceBiotech
In something of an understatement, Illumina CEO Francis deSouza said a 78% increase in second quarter sales over 2020 "significantly exceeded expectations" and has pushed the sequencing giant to raise its financial guidance for the remainder of the year.
August 4, 2021
news.google.com
The donation includes two of Illumina's newest next-generation sequencing platforms, the NextSeq 2000, reagents, a rapid bioinformatics analysis platform (DRAGEN) and four years of service support for the sequencing installations
Conor Hale
July 22, 2021
FierceBiotech
Illumina's antitrust troubles runneth over: The European Commission cited concerns that the vertical takeover of the DNA sequencing giant's former spinout could harm R&D efforts at competing diagnostic developers.
Conor Hale
July 15, 2021
FierceBiotech
Illumina may face a protracted legal battle with the EU over its takeover of the cancer test maker Grail unless it makes further concessions, according to a Reuters report.
Conor Hale
June 29, 2021
FierceBiotech
Element Biosciences has more than doubled its venture capital war chest, with the goal of offering low-cost, modular hardware in a DNA sequencing market dominated by a small number of players.
Conor Hale
June 25, 2021
FierceBiotech
The final results from a Grail study of its cancer-tracing blood test found it was accurate at detecting a range of different tumors at early stages--especially those more likely to be lethal and have fewer screening options.
Research and Markets
June 24, 2021
www.prnewswire.com:443
/PRNewswire/ -- The "Global Agrigenomics Market by Application (Crops and Livestock), Sequencer Type (Sanger Sequencing, Illumina HiSeq Family, PacBio...
Conor Hale
June 7, 2021
FierceBiotech
Currently available in the U.S. with a prescription, the Galleri test is meant to help screen people who may already have an elevated risk for cancer, such as adults over the age of 50.
Research and Markets
June 3, 2021
www.prnewswire.com:443
/PRNewswire/ -- The "Biotechnology Services Global Market Report 2021: COVID-19 Impact and Recovery to 2030" report has been added to ResearchAndMarkets.com's...
Conor Hale
June 2, 2021
FierceBiotech
Illumina's multibillion-dollar deal for cancer blood test developer Grail was already under an antitrust microscope in the U.S. and Europe. Now, the watchdogs in the States have raised a new threat--as the deal's closing deadline moves inexorably closer.
Global Market Insights Inc.
May 26, 2021
www.prnewswire.com:443
/PRNewswire/ -- According to the latest report, "PCR and NGS based Diagnostic Testing Market by Product (Consumables, Equipment, Labware), End-Use (Hospitals...
May 17, 2021
BioSpace
Illumina Appoints Susan Tousi as Chief Commercial Officer and Dr. Alex Aravanis as Chief Technology Officer, Head of Research and Product Development - read this article along with other careers information, tips and advice on BioSpace
Alex Keown
May 14, 2021
BioSpace
Biopharma and life sciences companies strengthen their leadership teams and boards with Movers & Shakers.
Jesse Lennox
May 5, 2021
Digital Trends
Some of the best pictures can't be taken until you've finished the game. Here's where you can snap a pic of all 10 of the Legendary Pokémon in New Pokémon Snap.
Conor Hale
April 29, 2021
FierceBiotech
To avoid fighting a two-front, international legal battle over its pursuit of the cancer tester Grail, Illumina has asked judges to step in and halt the European Commission's review of the proposed $8 billion deal.
Andrea Park
April 28, 2021
FierceBiotech
Amid the havoc wreaked around the world by the COVID-19 pandemic, the race is on to build better protections against future outbreaks. After dipping its toe in these waters with the launch of a pathogen-tracking initiative in Africa, Illumina is now fully diving in with a five-year commitment to a global version.
BioSpace
April 28, 2021
BioSpace
Illumina, Inc. (NASDAQ: ILMN) has committed US $60 million in sequencing capabilities to a global pathogen genomics initiative, in partnership with the Bill & Melinda Gates Foundation and other public and private entities
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References

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