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Pacific Biosciences

Pacific Biosciences

A biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation

OverviewStructured DataIssuesContributors

Contents

nanofluidics.com
pacb.com
pacificbiosciences.com
Is a
Company
Company
Organization
Organization

Company attributes

Industry
‌
Equipment
Engineering
Engineering
Technology
Technology
Proteomics
Proteomics
Biology
Biology
Biomedical engineering
Biomedical engineering
Biotechnology
Biotechnology
...
Location
Seoul
Seoul
Baltimore
Baltimore
0
Singapore
Singapore
0
United Kingdom
United Kingdom
San Francisco
San Francisco
China
China
Japan
Japan
San Diego
San Diego
0
...
B2X
B2B
B2B
CEO
Christian Henry
Christian Henry
Founder
Kevin Hester
Kevin Hester
Joseph Bonventre
Joseph Bonventre
Stephen Turner
Stephen Turner
AngelList URL
angel.co/pacific-biosciences0
Legal Name
Pacific Biosciences of California, Inc.
Subsidiary
Circulomics
Circulomics
Legal classification
Corporation
Corporation
Date Incorporated
2000
Number of Employees (Ranges)
201 – 500
Email Address
support@pacb.com0
orders@pacb.com0
Phone Number
+16505218000
Full Address
#10-117, WeWork Bldg, 507, Teheran-ro, Gangnam-gu, Seoul, Republic of Korea (06168)0
6965 Lusk Boulevard San Diego, CA 92121 USA0
20 Science Park Road, #01-22 Teletech Park, Singapore 117674 SG0
1305 O’Brien Drive Menlo Park, CA 94025 USA0
701 E. Pratt Street Baltimore, MD 21202 USA0
Ocean Gate, Mirato Mirai 8F 3-7-1 Minatomirai, Nishi-ku, Yokohama-shi Kanagawa 220-0012, JP0
Rolling Stock Yard 188 York Way London, N7 9AS UK0
Room 3256, 32F, No.222 East Yan’an Rd, Huangpu Distric, Shanghai, 200020, China0
CIK Number
1,299,130
Place of Incorporation
Delaware
Delaware
Investors
Mohr Davidow Ventures
Mohr Davidow Ventures
Intel Capital
Intel Capital
Morgan Stanley
Morgan Stanley
Alloy Ventures
Alloy Ventures
DAG Ventures
DAG Ventures
Sutter Hill Ventures
Sutter Hill Ventures
Kleiner Perkins Caufield & Byers
Kleiner Perkins Caufield & Byers
Gen-Probe
Gen-Probe
...
DUNS Number
149130325
IRS Number
161,590,339
Founded Date
January 1, 2004
Total Funding Amount (USD)
370,360,000
Latest Funding Round Date
2021
Stock Symbol
PACB
Exchange
Nasdaq
Nasdaq
Board of Directors
John F. Milligan
John F. Milligan
Bill Ericson
Bill Ericson
David Botstein
David Botstein
Randall S. Livingston
Randall S. Livingston
Lucy Shapiro
Lucy Shapiro
Hannah Valantine
Hannah Valantine
Kathy Ordoñez
Kathy Ordoñez
Christian Henry
Christian Henry
...
CTO
STEPHEN TURNER
STEPHEN TURNER
CFO
SUSAN KIM
SUSAN KIM
Key People
MARK VAN OENE
MARK VAN OENE
Christian Henry
Christian Henry
SUSAN KIM
SUSAN KIM
STEPHEN TURNER
STEPHEN TURNER
Latest Funding Type
‌
Series F
Patents Assigned (Count)
343
COO
MARK VAN OENE
MARK VAN OENE
Wellfound ID
pacific-biosciences
Country
Singapore
Singapore
0
China
China
0
Japan
Japan
0
South Korea
South Korea
0
United States
United States
0
United Kingdom
United Kingdom
0
Headquarters
Menlo Park, California
Menlo Park, California

Other attributes

Company Operating Status
Active0
Latest Funding Round Amount (USD)
900,000
SIC Code
3,826
Wikidata ID
Q2069106

Single Molecular Real-Time (SMRT) sequencing employs a specialized flow cell with many thousands of individual picolitre wells with transparent bottoms -- zero-mode waveguides (ZMW). The polymerase is fixed to the bottom of the well and allows the DNA strand to progress through the ZMW. As a result, the system can focus on a single molecular. SMRT sequencing allows for real-time imaging of fluorescently tagged nucleotides that are synthesized along individual DNA template molecules. The sequencing reaction ends when the template and polymerase dissociate. The average read length from the PacBio instrument is approximately 2 kb, and some reads may be over 20 kb. Longer reads are especially useful for de novo assemblies of novel genomes that can span many more repeats and bases.

Highly repetitive elements found in both eukaryotic and prokaryotic genomes pose a challenge for genome assembly and make the detailed study of repetitive sequences difficult. Long-read sequencing delivers reads in excess of several or dozens of kilobases (kbs), which can span complex or repetitive regions with a single continuous read, allowing for the resolution of these large structural features. Besides considerably longer and highly accurate DNA sequences from individual unamplified molecules, it can also exhibit where methylated bases occur, thereby providing functional information about DNA methyltransferases encoded by the genome.

Pacific Biosciences provides genomic analysis systems that deliver insights for scientists who strive to resolve complex genetic challenges. PacBio sequencing offers views of genomes, transcriptomes, and epigenomes.

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Funding Rounds

Products

Acquisitions

SBIR/STTR Awards

Patents

Further Resources

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