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Cluster: Biotechnology

Cluster: Biotechnology

A cluster of topics related to biotechnology.

Biotechnology is the use of technology to modify or manipulate living systems or parts of living systems for the generation of useful products, biological processing, to treat disease or to acquire knowledge. Products manufactured or processed using biotechnology are found in agricultural, pharmaceutical, food, chemical and biofuel industries. Biotechnology is also used in waste treatment.

Biotechnology fundamentals

Biotechnology is used to modify living systems or parts of living systems based on knowledge about essential parts or processes which allow living things to grow, reproduce, use resources and respond to their environment.

Biotechnology tools

Biotechnology tools have been developed in research areas such as molecular biology, biochemistry, immunology, genetics, microbiology, cell biology and agriculture.

Nucleic acid sequencing
Gene editing tools
Biomaterials

Biomaterials interact with biological systems. They can be natural or synthetic, alive or lifeless and are made of multiple components. Biomaterials are often used in medical applications.

Biomolecules

Biomolecules, also called biological molecules, are molecules produced by cells of living organisms. DNA, RNA and enzymes are examples of biomolecules. The following are biomolecules with uses in pharmaceuticals, food, cosmetics or textiles.

Mapping Projects

Mapping projects serve as reference manuals to living systems by showing the organization of components within living organisms. Mapping projects promote the sharing of biological information.

Standardization
Facilitating access to DNA sequences
Large biopharmaceutical companies
Therapeutics companies

The following companies are using biotechnology in disease research and in development and production of medicine or therapies for a range of injuries or illnesses.

Allergy
Diabetes
Herpes
Software
Drug delivery system
Drug discovery platforms
Kidney disease
Pain treatment
Dermatology
Cancer
Immunotherapy
Rare disease
Therapeutics targeting RNA splicing
Multi-drug resistant bacteria
ADHD treatment
Depression and anxiety
Autoimmune and inflammatory disease
Respiratory and pulmonary disease
Cardiovascular disease
Contract research companies
Regenerative medicine
Neuromuscular disease
Alzheimer's, neurological and neurodegenerative diseases
Infertility
Contraceptives
Eye disease or injury
Bone repair and sports medicine
Eating disorders
Antibacterial products and therapeutics
Aging
Fibrosis
Plant-based manufacturing of therapeutics and vaccines
Live bacteria therapeutic delivery systems
Genome editing and gene therapy
Drug discovery in microbes
Vaccines and treatments for infectious disease
Theranostics

Theranostics combines diagnotics and therapeutics.

In vitro diagnostics (IVD) and molecular diagnostics companies

Biotechnology is used by IVD companies to develop tests that detect diseases in vitro, meaning outside the body, from human samples like blood, urine and tissue. Molecular diagnostics are a subset of tests within IVD which detect DNA and RNA in order to assess health. Examples are detection of disease-causing gene mutations or presence of viral DNA or RNA. Detection of proteins using antibodies is considered separate from molecular diagnostics but falls under IVD. In addition to molecular diagnostics and immunoassays, the IVD market also includes clinical chemistry, hematology analyzers and microbiology culture.

Diagnostics tools
  • Cas12a based DETECTR system to detect viruses
  • Cas12a based HOMES system to detect viruses and small nucleotide polymorphism sites in human DNA related to health and personal characteristics
  • CRISPR-on-a-chip for cancer diagnostics
Advising oncology treatment based on molecular tests

Personalized health and disease risk testing
Genetic Testing for Disease Risks
Epigenetic Testing for Disease Risks
Large Genomics and Health Studies
Genomic analysis for drug development and deployment
Microbiome analysis
Proteomics-based biomarkers
RNA-based biomarkers
Quantum computing applications in life sciences
Genetic ancestry testing
  • 23andMe
  • Ancestry
  • HomeDNA
  • Living DNA
  • Gene-by-Gene provides Family Tree DNA
  • Gene-by-Gene runs the Genographics Project labs which uses the National Geographic Geno DNA Kit
  • African Ancestry
  • Full Genomes
  • DNA Tribes
Imaging technology and bioanalytics
Bioprinting
  • Vivax Bio and its subsidiary, 3D Bioprinting Solutions
Biotechnology companies that provide research tools

The following companies that produce instruments, kits, reagents and computer software for basic and applied biological research.

Microfluidic cell culture, organ-on-a-chip, human-on-a-chip
Sustainable and biodegradable materials
Food industry
Textiles
Chemical industry
Agriculture (Ag biotech)
Biological control systems
  • Oxitec (insect-based control of disease-carrying mosquitoes and crop-damaging insects)
Carbon capture and conversion
Floriculture
Biofuels

First generation biofuels include ethanol and plant oil produced from sugar and starch. Second generation biofuels are produced from non-food biomass called lignocellulose and are called cellulosic biofuels. Third generation biofuels are derived from algae and produce feedstock as well as fuel. Fourth generation biofuels are electrofuels or photobiological solar fuels.

Biomining and bioremediation
Wetware
Biotechnology in conservation
Skincare products
Blockchain and biology

The ability of blockchain to facilitate transparency, control and sharing of information, while keeping data secure, is being applied to biotechnology. Blockchain technology in data storage and online platforms can improve sharing and access to information and also provide quicker ways for tracking and managing various steps in drug development.

 For immunotherapies such as CAR-T cell therapy, blockchain can provide ways to store, maintain, track and secure information about cells derived from a donor patient like editing performed, storage conditions and transport from donor to recipient. Information must be accessible to patients, physicians, laboratory scientists, logistics companies, supply chains and infusion centers.

Other biotechnology companies
Trade Associations
Biotechnology investment
Biotech startup support
Consultants in Biotechnology
Research Institutes
Community biolabs and projects
Conferences
  • Transtech Conference
  • International Conference on Biomedical Engineering and Biotechnology
  • Discovery On Target
  • BIO-Europe
  • Biotech Showcase
  • Cell Series USA
  • The American Society of Human Genetics annual meeting
  • The American Society for Cell Biology annual meeting
Biosafety organizations

Timeline

People

Name
Role
LinkedIn

Further reading

Title
Author
Link
Type
Date

1H 2019 biopharma startup and VC report

Richard Murphey

Web

7/9/2019

Documentaries, videos and podcasts

Title
Date
Link

Companies

Company
CEO
Location
Products/Services

Santa Cruz, CA

Nanopore Detection Platform

News

Title
Author
Date
Publisher
Description
FE Online
August 26, 2021
The Financial Express
The Department of Biotechnology (DBT) has said that ZyCoV-D is the world's first DNA-based vaccine against the coronavirus and when injected produces the spike protein of the SARS-CoV-2 virus and elicits an immune response, which plays a vital role in protection from the disease as well as viral clearance.
August 26, 2021
The Weather Channel
It is a game-changer as it is an intradermal vaccine and will help those hesitant to take an injection. - Articles from The Weather Channel | weather.com
Livemint
August 23, 2021
mint
Govt looking at developing a vaccine that can be pan-corona so that if any other virus comes in then the vaccine can respond to it
August 21, 2021
NDTV.com
Zydus Cadila, whose Covid vaccine ZyCoV-D for adults and children aged 12 years and above got approval yesterday, said it hopes to produce one crore doses per month by October.
BS Web Team & Reuters
August 20, 2021
@bsindia
Adolescents in the age group of 12-18 years can take the shot in India
Karthikeyan
July 4, 2021
dtNext.in
ICMR study also states 58% didn't show antibodies after 1st Covishield jab
Science X staff
June 29, 2021
phys.org
The research team of Professor Toshihiko Eki of the Department of Applied Chemistry and Life Science (and Research Center for Agrotechnology and Biotechnology), Toyohashi University of Technology used a next-generation sequencer to develop a highly efficient method to analyze soil nematodes by using the 18S ribosomal RNA gene regions as DNA barcodes.
June 17, 2021
WebWire
• The results are part of the first study analysing diversity in the Spanish investing ecosystem, prepared by the international non-profit Diversity VC, which is supported by CaixaBank through DayOne, and Osborne Clarke., , , , • The sectors with the highest female representation in decision-making positions are Social Impact (31.6%) and Biotechnology (24.4%)., , , , • As part of the study, information from 86 firms in Spain's investing ecosystem was analysed, including 58 venture capital firms, 1...
BioSpace
June 14, 2021
BioSpace
Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) today announced that Executive Vice President and Chief Scientific Officer C. Frank Bennett, Ph.D., is a co-recipient of the 23rd Jacob and Louise Gabbay Award in Biotechnology and Medicine for his innovative work on antisense therapy.
Ionis Pharmaceuticals, Inc.
June 14, 2021
www.prnewswire.com:443
/PRNewswire/ -- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) today announced that Executive Vice President and Chief Scientific Officer C. Frank Bennett, Ph.D.,...
Press Trust of India
April 29, 2021
@bsindia
Biocon has reported 86.29% jump in consolidated profit to Rs 296.4 crore for the quarter ended March 31, 2021
Research and Markets
April 22, 2021
www.prnewswire.com:443
/PRNewswire/ -- The "Animal Biotechnology - Technologies, Markets and Companies" report from Jain PharmaBiotech has been added to ResearchAndMarkets.com's...
March 2, 2021
The Economic Times
The policy, which looks to consolidate the states position as a global hub for engineering R&D, has been drafted by the Department of IT and Biotechnology and seeks to offer multinational companies the option of either setting up new ER&D units or expanding their existing facilities.
Research and Markets
January 25, 2021
www.prnewswire.com:443
/PRNewswire/ -- The "Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems" report has been added to ResearchAndMarkets.com's offering....
Bharath Manjesh
January 5, 2021
@bsindia
Other vaccines being developed in India, dangerous conspiracy theories, private hospitals keen on jumping in-news relevant to Indias fight against Covid-19
December 26, 2020
The Economic Times
Variations in gene sequences will keep happening as the virus spreads across the globe, says principal scientific adviser K VijayRaghavan. About 5,879 variants of SARSCoV-2 exist in India itself.
Valuates Reports
December 18, 2020
www.prnewswire.com:443
/PRNewswire/ -- The Biochips Market is Segmented by Type (DNA Chip, Lab-on-a-Chip, Protein Chip, Others), By Application (Biotechnology and Pharmaceutical...
Press Trust of India
December 17, 2020
@bsindia
Over 100 experts from friendly neighbouring nations have so far been trained to strengthen capacities in their countries for facilitating phase-3 clinical trials of Indian Covid-19 vaccine
Boris Babic
December 1, 2020
Harvard Business Review
Or, for that matter, a Covid-19 vaccine?
Press Trust of India
August 24, 2020
@bsindia
A Mission COVID Suraksha has been proposed to be set up with a corpus of nearly Rs 3,000 crore, sources said.
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