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RNA

RNA

RNA stands for ribonucleic acid. Messenger RNA (mRNA) is copied or transcribed from DNA and carries the coding information for the generation of a protein encoded by a gene. Different types of non-coding RNAs have roles in converting mRNA into protein and perform other regulatory functions in the cell.

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Science X staff
August 3, 2021
phys.org
In the latest of ongoing efforts to expand technologies for modifying genes and their expression, researchers in the lab of Neville Sanjana at New York University (NYU) and the New York Genome Center (NYGC) have developed chemically modified guide RNAs for a CRISPR system that targets RNA instead of DNA. These chemically modified guide RNAs significantly enhance the ability to target--trace, edit, and/or knockdown--RNA in human cells.
Sarfaraz K. Niazi, PhD
July 31, 2021
The Center For Biosimilars
Sarfaraz K. Niazi, PhD, discusses the regulatory approval of future messenger RNA vaccines, which will likely face fewer patent issues and are easy to replicate.
Science X staff
July 30, 2021
phys.org
Hokkaido University researchers in Japan created and tested a library of lipid-based compounds to find a way to safely and effectively deliver RNA drugs to the lungs. Their analyses, published in the journal Materials Horizons, pinpointed a lipid polymer that might in the future be used to treat acute respiratory distress syndrome, pulmonary hypertension and lung cancers.
Meagan Simpson
July 28, 2021
BetaKit
Deep Genomics has secured $226 million CAD as the startup has increased the number of drug candidates it has discovered using AI and is eyeing clinic trials.
Conor Hale
July 28, 2021
FierceBiotech
With the performance of COVID-19 vaccines making RNA-based medicines a household name, Deep Genomics is reaping some of the buzz--as well as $180 million in new funding for its efforts.
July 26, 2021
The Indian Express
The team also identified infected host cells and pathways associated with protection against infection.
The Pioneer
July 26, 2021
The Pioneer
The course of severe COVID-19 may be determined by the body's antiviral response to initial infection, according to a study which opens up new avenues for early drug interventions that could prevent severe disease. Researchers from Massachusetts Institute of Technology (MIT) and Harvard University
Science X staff
July 22, 2021
phys.org
Manipulating RNA can allow plants to yield dramatically more crops, as well as increasing drought tolerance, announced a group of scientists from the University of Chicago, Peking University and Guizhou University.
Science X staff
July 22, 2021
phys.org
Advances in microscopy have enabled researchers to picture loops of DNA strands for the first time. The images reveal how the human genome organizes itself in three-dimensional space at much higher resolution than previously possible.
Science X staff
July 21, 2021
phys.org
Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever. Now, researchers reporting in ACS' Journal of Proteome Research have analyzed viral proteins across 27 coronavirus species and thousands of samples from COVID-19 patients, identifying highly conserved sequences that could make the best drug targets.
Science X staff
July 20, 2021
phys.org
When SARS-CoV-2 infects a cell, it introduces its RNA into it and re-programs it in such a way that the cell first produces viral proteins and then whole viral particles. In the search for active substances against SARS-CoV-2, researchers have so far mostly concentrated on the viral proteins and on blocking them, since this promises to prevent, or at least slow down, replication. But attacking the viral genome, a long RNA molecule, might also stop or slow down viral replication.
July 19, 2021
News-Medical.net
In February 2020, a trio of bio-imaging experts were sitting amiably around a dinner table at a scientific conference in Washington, D.C., when the conversation shifted to what was then a worrying viral epidemic in China.
Aliyah Kovner
July 19, 2021
phys.org
In February 2020, a trio of bio-imaging experts were sitting amiably around a dinner table at a scientific conference in Washington, D.C., when the conversation shifted to what was then a worrying viral epidemic in China. Without foreseeing the global disaster to come, they wondered aloud how they might contribute.
Liu Jia
July 19, 2021
phys.org
Thousands of proteins undergo arginine N-methylation, a widespread post-translational modification catalyzed by several protein arginine methyltransferases (PRMTs) that covalently link methyl groups to arginine side chains. Nine PRMTs, PRMT1 to PRMT9, have been identified in the human genome, which are further classified into three types according to the final methylarginine products. Arginine methylation plays key roles in various cellular processes.
Science X staff
July 16, 2021
phys.org
The ability to predict and interpret modifications of ribonucleic acid (RNA) has been a welcome advance in biochemistry research.
Andrew Lyle
July 16, 2021
phys.org
A new study by University of Alberta biophysicists has revealed how a rare structure forms within RNA from the Zika virus that makes it resistant to our bodies' immune systems. The results provide a potential target for new drug therapies to combat the virus and others like it.
Amirah Al Idrus
July 15, 2021
FierceBiotech
Shape Therapeutics is ramping up its RNA-editing technologies with a $112 million round from the likes of Decheng Capital, Breton Capital and New Enterprise Associates. In addition to supporting the development of multiple RNA platforms, the proceeds will also bankroll partnership opportunities for the Seattle-based biotech.
Science X staff
July 15, 2021
phys.org
A small regulatory RNA found in many problematic bacteria, including Escherichia coli, appears to be responsible for managing the response of these bacteria to environmental stresses. Professor Charles Dozois from Institut national de la recherche scientifique (INRS) and doctoral student Hicham Bessaiah see a promising avenue for more effective treatment of antibiotic-resistant bacteria. Their results have been published in the journal PLOS Pathogens.
FinSMEs
July 12, 2021
FinSMEs
About | Advertise | Contact | Disclaimer | News | The Daily Deal Newsletter FinSMEs.com by FinSMEs is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
July 10, 2021
Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been detected in untreated and treated wastewater and studies have shown that the concentration of SARS-CoV-2 is proportional to the p...
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