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Deborah Crouch

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Dima Kobko
edited on 26 May, 2022
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Edits on 14 Dec, 2021
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edited on 14 Dec, 2021
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Patent primary examiner of
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US Patent 7094400 Transkaryotic implantation
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US Patent 7094949 Breeding and milking cows for milk free of β-casein A
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US Patent 7105717 Model rat with the onset of prostatic cancer
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US Patent 7122714 Mouse models of human prostate cancer
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US Patent 7126039 Animal tissue with carbohydrate antigens compatible for human transplantation
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US Patent 7141551 Wound and cutaneous injury healing with a nucleic acid encoding perlecan
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US Patent 7150989 Telomerase immortalized neural progenitor cells
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US Patent 7161057 Animal model having a chimeric human liver
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US Patent 7166764 Noc2 knockout mouse
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US Patent 7169963 Mammals expressing IGF-1 and alpha-lactalbumin in their milk
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US Patent 7179953 Monitoring APP cleavage in transgenic rodents comprising an APP-Swedish mutation
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US Patent 7186521 Determining the effect of a substance on sequestration, uptake, and accumulation of amyloid in brain cells
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US Patent 7186879 Screening systems and methods for identifying modulators of xenobiotic metabolism
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US Patent 7186881 Testing compounds for effects on synaptophysin in transgenic mice expressing an Alzheimer's disease FAD DNA sequence
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US Patent 7193125 Screening systems and methods for identifying modulators of xenobiotic metabolism
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US Patent 7195911 Mammalian cells that have increased proliferative capacity
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US Patent 7196069 High affinity RNA ligands of basic fibroblast growth factor
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US Patent 7202227 Multifunctional molecular complexes for gene transfer to cells
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US Patent 7205148 Genome mutation by intron insertion into an embryonic stem cell genome
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US Patent 7214850 Transgenic mouse expressing Prkag3
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US Patent 7217569 Clonal cultures of primate embryonic stem cells
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US Patent 7220584 Method of making embryoid bodies from primate embryonic stem cells
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US Patent 7223740 Vectors for enhanced expression of VEGF for atrial disease treatment
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US Patent 7230156 Method for preparing a sterile transgenic carp
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US Patent 7232938 Cloning ungulates from a quiescent donor cell
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US Patent 7238851 Non-human transgenic mammals expressing an n-3 desaturase gene
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US Patent 7244423 Methods for therapy of neurodegenerative disease of the brain
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US Patent 7250551 Transgenic mice expressing inducible human p25
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US Patent 7252989 Adenovirus supervector system
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US Patent 7259291 Enucleation of avian eggs by gamma irradiation
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US Patent 7264969 Carrier system for specific artery wall gene delivery
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US Patent 7265259 GSK-3β expressed in a transgenic mouse
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US Patent 7265262 Telomerizing nuclear donor cells and improving the efficiency on nuclear transfer
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US Patent 7267981 Human foreskin fibroblasts for culturing ES cells
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US Patent 7271001 Method for mitochondrial targeting of p53
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US Patent 7276644 Transgenic mouse comprising a myosin heavy chain atpase loop 1 mutation
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US Patent 7279326 Composition for delivery of a mitochondrial genome to a cell
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US Patent 7285699 Ends-out gene targeting method
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US Patent 7291764 Cloning pigs using non-quiescent differentiated donor cells or nuclei
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US Patent 7297836 Methods of detecting neurological disorders
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US Patent 7304040 Suppression of post-transplant arteriosclerosis
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US Patent 7304204 Ungulates produced by nuclear transfer of G1 cells
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US Patent 7307198 Ungulates produced by nuclear transfer of G1 cells
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US Patent 7309811 Transgenic mice knockouts of BACE-1
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US Patent 7319094 Increased and sustained in vivo gene expression using a nucleic acid, histone and amphipathic compound composition
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US Patent 7321075 Serial nuclear transfer of ungulate embryos
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US Patent 7321076 Unactivated ungulate oocytes to produce a cloned ungulate by nuclear transfer
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US Patent 7323337 Gene transfer into primate embryonic stem cells using VSV-G pseudotyped simian immunodeficiency virus vectors
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US Patent 7323616 Genetically altered mice deficient in functional caspase-9
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US Patent 7326572 Endoderm cells from human embryonic stem cells
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US Patent 7326824 Unactivated ungulate oocytes to produce a transgenic ungulate by nuclear transfer
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US Patent 7326825 Methods of ungulate nuclear transfer
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US Patent 7329796 Serial nuclear transfer of ungulate embryos
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US Patent 7332648 Unactivated oocytes in nuclear transfer to produce cultured inner cell mass cells and ungulates
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US Patent 7351874 Mouse model for fatty acid amide-related neurobehaviors
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US Patent 7354594 Merozoite surface protein 1 lacking glycosylation sites
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US Patent 7354763 Generating vascular smooth muscle cells in vitro from ES cells
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US Patent 7355094 Methods of ungulate nuclear transfer
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US Patent 7358234 Induction of a protective immune response through microprojectiles coated with a DNA sequence encoding an immunogenic protein
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US Patent 7361684 Screening of compounds for treatment of atherosclerosis and heart attack
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US Patent 7361804 Unactivated oocytes in nuclear transfer to produce ungulates
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US Patent 7371922 Nuclear transfer with porcine embryonic stem cells
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US Patent 7381710 Combined DNA vaccine and biological modifiers for cancer therapy
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US Patent 7390657 Method for generating primate trophoblasts
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US Patent 7402308 Method of delivering genes to the central nervous system of a mammal
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US Patent 7405342 Transgenic mice expressing heterologous complement receptor type 1 (CR1) molecules on erythrocytes and uses therefor
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US Patent 7411111 Method for cloning of the rat by nuclear transfer
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US Patent 7413902 Feeder-free culture method for embryonic stem cells or primate primordial stem cells
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US Patent 7414032 Vaccine comprising a polynucleotide encoding an antigen recognized by a CD4
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US Patent 7414170 Transgenic bovines capable of human antibody production
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US Patent 7419948 Treatment of hemophilia with human Factor IX produced in mammary tissue of transgenic mammals
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US Patent 7427396 AAV vectors for gene delivery to the lung
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US Patent 7429690 Transgenic bovines having reduced prion protein production
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US Patent 7432104 Methods for the culture of human embryonic stem cells on human feeder cells
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US Patent 7432414 Transgenic mouse having an amyloid precursor protein with a modified beta secretase cleavage site
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US Patent 7432415 Unactivated oocytes as cytoplast recipients for nonprimate mammalian and pig nuclear transfer
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US Patent 7435869 Transgenic nonhuman mammals producing fibrinogen in milk and methods of producing fibrin
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US Patent 7439064 Cultivation of human embryonic stem cells in the absence of feeder cells or without conditioned medium
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US Patent 7442548 Culturing human embryonic stem cells in medium containing pipecholic acid and gamma amino butyric acid
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US Patent 7446240 Method for the production of porcine nuclear transfer embryos
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US Patent 7449334 Medium containing pipecholic acid and gamma amino butyric acid and culture of embryonic stem cells
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US Patent 7449449 Particle-mediated transformation of vertebrate tissue cells
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US Patent 7465582 Nurr-1 induction of a dopaminergic neuronal fate in a neural stem cell or neural progenitor cell in vitro
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US Patent 7468242 Dermal micro organs, methods and apparatuses for producing and using the same
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US Patent 7468277 Enriched preparation of human fetal multipotential neural stem cells
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US Patent 7476536 Artificial human chromosome containing human antibody a light chain gene
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US Patent 7479579 Triple transgenic mouse model of Alzheimer's disease
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US Patent 7488719 Wound and cutaneous injury healing with a nucleic acid encoding perlecan
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US Patent 7491865 Mouse models of prostate cancer development and metastasis through expression of a hepsin transgene
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US Patent 7491867 Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates
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US Patent 7495147 Neuregulin-1 transgenic mouse and methods of use
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US Patent 7501553 Non-human transgenic mammal comprising a modified MSP-1 nucleic acid
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US Patent 7514258 Mammalian cultured inner cell mass cell culture using a quiescent cell as nuclear
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US Patent 7514592 Inducible heart attack animal model
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US Patent 7521590 Phospholipase C β1 (PLCβ1) knockout mice as a model system for testing schizophrenia drugs
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US Patent 7524490 Clusterin-mediated inhibition of apoptosis via stromal bone marrow cell delivery to a cardiac site
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US Patent 7524677 Mammalian cultured inner cell mass cell culture using a g1 cell as nuclear donor
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US Patent 7527974 Embryonic stem cells derived from human somatic cell—rabbit oocyte NT units
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US Patent 7534774 Traversal of nucleic acid molecules through a fluid space and expression in repair cells
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US Patent 7538258 Transgenic mouse expressing an APP 670/671 mutation
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US Patent 7541183 Growth and differentiation of adult muscle stem cells with activators or inhibitors of Wnt signaling
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US Patent 7544853 C1 inhibitor with short half-life transient treatment
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US Patent 7544854 Transgenic non-human animals for pharmacological and toxicological studies
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US Patent 7547522 Method to enrich for α(1,3)-galactosyltransferase null pig cells
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US Patent 7547545 Directed in vitro differentiation of marrow stromal cells into neural cell progenitors
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US Patent 7547549 Method to produce a hybrid cell having a single mitochondrial genotype
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US Patent 7547816 α(1,3)-galactosyltransferase knockout swine, tissues and organs
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US Patent 7547818 Metaphase donor cells for effective nuclear reprogramming in mammals
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US Patent 7550647 Transfected shrimp as production systems for therapeutic proteins
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US Patent 7550648 Inducing neurofibrillary tangles in transgenic mice expressing a mutant tau protein
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US Patent 7560279 Method of proliferating human hepatocytes and method for obtaining human hepatocytes
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US Patent 7563575 Breeding and milking cows for milk free of β-casein A
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US Patent 7563598 Detection of truncation mutations by mass spectrometry
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US Patent 7575921 Spore-like cells and uses thereof
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US Patent 7576065 Enhancing neurotrophin-induced neurogenesis by endogenous neural progenitor cells by concurrent overexpression of brain derived neurotrophic factor and an inhibitor of a pro-gliogenic bone morphogenetic protein
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US Patent 7582479 Primate embryonic stem cell line
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US Patent 7592175 Methods of preparing feeder cells-free, xeno-free human embryonic stem cells and cell cultures prepared using same
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US Patent 7592176 Method of forming mesenchymal stem cells from embryonic stem cells
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US Patent 7592503 Mammalian telophase oocyte enucleation
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US Patent 7595303 Genetic adjuvants for immunotherapy
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US Patent 7598079 Assay for identifying compounds which affect stability of mRNA
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US Patent 7598082 Process of mammalian cell reprogramming through production of a heterokaryon
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US Patent 7598228 Therapeutic methods and agents for diseases associated with decreased expression of AOP-1 gene or AOP-1
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US Patent 7608451 Gene regulation in transgenic animals using a transposon-based vector
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US Patent 7608749 Monitoring APP cleavage in transgenic rodents comprising an APP Swedish mutation
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US Patent 7622630 Chimeric cancer models
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US Patent 7625753 Expansion of definitive endoderm cells
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US Patent 7642402 Human photoaged skin model
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US Patent 7652191 Nonhuman mammals exhibiting PTSD-like behavior
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US Patent 7652192 Cloning of transgenic unglulates comprising artificial chromosomes
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US Patent 7662625 Methods for detecting the differentiation status of cells using 5T4 antigen expression
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US Patent 7663018 Tau hyperphosphorylation in transgenic mice expressing the APP double mutation
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US Patent 7663019 Transgenic snakes and methods of making
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US Patent 7674454 Enzyme-prodrug therapy for prosthetic joint repair
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US Patent 7682825 Differentiation of bone marrow stromal cells to neural cells or skeletal muscle cells by introduction of notch gene
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US Patent 7683236 Enhanced production of cloned mammals by zona pellucida-free homologous mammalian embryo aggregation
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US Patent 7687266 Pluripotency determining factors and uses thereof
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US Patent 7700352 Composition for culturing mouse pluripotent stem cells
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US Patent 7700822 Modulation of cytochrome P450 reductase activity
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US Patent 7700823 Transgenic animals exhibiting major disorders related to Alzheimer's disease
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US Patent 7704492 Methods for delivering DNA to muscle cells using recombinant adeno-associated virus virions
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US Patent 7709695 Transgenic mouse expressing arctic mutation E693G
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US Patent 7718845 Production of growth hormone in the milk of a transgenic bovine and methods of purification of the growth hormone from the milk
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US Patent 7732202 Oxygen tension for the parthenogenic activation of human oocytes for the production of human embryonic stem cells
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US Patent 7741079 Method of making a genetically modified mammalian cell
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US Patent 7745688 Model mouse of Alzheimer's disease expressing FAD APP 716 and use thereof
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US Patent 7754467 Surface expression of biologically active proteins in bacteria
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US Patent 7759118 Proliferation of hepatocyte precursors
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US Patent 7759542 Glycine N-methyltransferase (GNMT) animal model and use thereof
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US Patent 7763462 BDNF facilitation of oocyte, zygote and pre-implantation embryo maturation
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US Patent 7767201 Vascular cells genetically altered to over-express angiogenic proliferation and maturation factors; treatment of atherosclerosis using same
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US Patent 7772001 Directed differentiation of embryonic stem cells into an endoderm cell
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US Patent 7772204 Perlecan and growth factor for wound and cutaneous injury healing
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US Patent 7781216 Spontaneous differentiation of human embryonic stem cells in culture
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US Patent 7781574 Chimeric osteogenic factor containing proteins capable of increased nuclear localization and methods of use thereof
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US Patent 7785792 Targeted modification of chromatin structure
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US Patent 7790451 HSV with a Musashi promoter regulating γ34.5 and ribonucleotide reductase expression
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US Patent 7790455 Human foreskin fibroblast conditioned media for culturing ES cells
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US Patent 7790458 Material and methods for the growth of hematopoietic stem cells
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US Patent 7795023 Identification of a pluripotent pre-mesenchymal, pre-hematopoietic progenitor cell
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US Patent 7795026 Methods for obtaining human embryoid body-derived cells
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US Patent 7799969 Methods for cloning rats by nuclear transfer
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US Patent 7803981 Transgenic ungulates capable of human antibody production
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US Patent 7807146 Methods for treating cancer with a recombinant MVA expressing HER-2
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US Patent 7807862 Transgenic bovine comprising human growth hormone in its serum and methods of making
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US Patent 7807863 Transgenic bovine having reduced prion protein activity and uses thereof
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US Patent 7811603 Microfluidic device for forming monodisperse lipoplexes
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US Patent 7816136 Method for growing stem cells on genetically modified supporter cells
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US Patent 7820439 In vitro generation of GABAergic neurons from pluripotent stem cells
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US Patent 7829078 Methods of treating anemia using recombinant adeno-associated virus virions
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US Patent 7834239 Sale of transgenic fish that express gene encoding fluorescent protein
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US Patent 7863002 Breeding and milking cows for milk free of β-casein A
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US Patent 7867487 Method for treating inflammation associated with amyloid deposits and brain inflammation involving activated microglia
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US Patent 7867974 Induction of tolerance by oral administration of factor VIII and treatment of hemophilia
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US Patent 7888321 Production of high levels of transgenic factor IX without gene rescue, and its therapeutic uses
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US Patent 7906330 Two cell population comprising chondrocyte precursors and human embryonic stem cells
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US Patent 7928064 Transgenically produced antithrombin III
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US Patent 7928283 Transgenic reporter system that reveals expression profiles and regulation mechanisms of alternative splicing in nematodes
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US Patent 7939322 Cells expressing pluripotency markers and expressing markers characteristic of the definitive endoderm
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US Patent 7943293 Media solutions and methods for cryopreservation and thawing of in vitro fertilization specimens
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US Patent 7947501 Gene recombination exchange system for stable gene modification in human ES cells
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US Patent 7951585 Construction of oncolytic adenovirus recombinant specifically expressing immune modulatory factor GM-CSF in tumor cells and uses thereof
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US Patent 7951591 Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues
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US Patent 7955851 Culture of human embryonic stem cells on a matrix with TGFB1 and bFGF
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US Patent 7964394 Spore-like cells and uses thereof
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US Patent 7964401 Screening method for somatic cell nuclear reprogramming substance affecting ECAT2 and ECAT3
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US Patent 7972849 Primate pluripotent stem cells produced by somatic cell nuclear transfer
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US Patent 7981630 CBARA1 and LHX6 cell markers for embryonic stem cells
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US Patent 8007780 AAV vectors for gene delivery to the lung
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US Patent 8008539 Generation of transgenic human soluble amyloid precursor protein alpha expressing mice
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US Patent 8013208 Methods for producing antibodies
Edits on 13 Dec, 2021
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edited on 13 Dec, 2021
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US Patent 8013208 Methods for producing antibodies
Edits on 8 Dec, 2021
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Golden AI
edited on 8 Dec, 2021
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Patent primary examiner of
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US Patent 8008539 Generation of transgenic human soluble amyloid precursor protein alpha expressing mice
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Golden AI
edited on 8 Dec, 2021
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Patent primary examiner of
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US Patent 8007780 AAV vectors for gene delivery to the lung
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Golden AI
edited on 8 Dec, 2021
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Patent primary examiner of
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US Patent 7981630 CBARA1 and LHX6 cell markers for embryonic stem cells
Edits on 8 Dec, 2021
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Golden AI
edited on 8 Dec, 2021
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Patent primary examiner of
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US Patent 7972849 Primate pluripotent stem cells produced by somatic cell nuclear transfer
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Golden AI
edited on 8 Dec, 2021
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Golden AI
edited on 8 Dec, 2021
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Patent primary examiner of
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US Patent 7964394 Spore-like cells and uses thereof
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Golden AI
edited on 7 Dec, 2021
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Patent primary examiner of
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US Patent 7955851 Culture of human embryonic stem cells on a matrix with TGFB1 and bFGF
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edited on 7 Dec, 2021
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edited on 7 Dec, 2021
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edited on 7 Dec, 2021
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Patent primary examiner of
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US Patent 7947501 Gene recombination exchange system for stable gene modification in human ES cells
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edited on 7 Dec, 2021
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edited on 7 Dec, 2021
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edited on 7 Dec, 2021
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Patent primary examiner of
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US Patent 7928064 Transgenically produced antithrombin III
Edits on 7 Dec, 2021
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Golden AI
edited on 7 Dec, 2021
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Patent primary examiner of
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US Patent 7906330 Two cell population comprising chondrocyte precursors and human embryonic stem cells
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edited on 6 Dec, 2021
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Golden AI
edited on 6 Dec, 2021
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Patent primary examiner of
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US Patent 7867974 Induction of tolerance by oral administration of factor VIII and treatment of hemophilia

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