US Patent 7232938 Cloning ungulates from a quiescent donor cell

Patent 7232938 was granted and assigned to Roslin Institute on June, 2007 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Roslin Institute

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7232938

Date of Patent

June 19, 2007

Patent Application Number

10915338

Date Filed

August 11, 2004

Patent Primary Examiner

‌

Deborah Crouch

Patent abstract

A method of reconstituting an animal embryo involves transferring the nucleus from a quiescent donor cell into a suitable recipient cell. The donor cell is quiescent, in that it is caused to exit from the growth and division cycle at G1 and to arrest in the G0 state. Nuclear transfer may take place by cell fusion. The reconstituted embryo may then give rise to one or more animals. The invention is useful in the production of transgenic animals as well as non-transgenics of high genetic merit.