US Patent 7759542 Glycine N-methyltransferase (GNMT) animal model and use thereof

Patent 7759542 was granted and assigned to National Yang-Ming University on July, 2010 by the United States Patent and Trademark Office.

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Patent

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Current Assignee

National Yang-Ming University

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

77595420

Patent Inventor Names

Yi-Ming Chen0

Shih-Ping Liu0

Date of Patent

July 20, 2010

Patent Application Number

118323040

Date Filed

August 1, 2007

Patent Primary Examiner

‌

Deborah Crouch

Patent abstract

The present invention is a new type of Glycine N-methyltransferase (GNMT) knockout mice model. This model can be applied to screen drug, test of treatment and search for diagnostic marker of hepatocellular carcinoma (HCC), glycogen storage disease, liver dysplasia, fatty liver and other liver disease.

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