Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 19, 2008
Patent Application Number
10441503
Date Filed
May 19, 2003
Patent Primary Examiner
Patent abstract
The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy chain expression and, optionally, by inactivation of Ig light chain expression, and by the further introduction of an artificial chromosome which results in the expression of xenogenous antibodies (e.g., non-bovine antibodies), preferably human antibodies.
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