Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 7, 2007
Patent Application Number
08222285
Date Filed
April 4, 1994
Patent Primary Examiner
Patent abstract
An adenoviral supervector system is disclosed that is capable of expressing more than 7.5 kilobases of heterologous DNA in a replication defective adenoviral vector. The supervector system comprises an adenoviral vector construct and a helper cell. The vector construct is capable of being replicated and packaged into a virion particle in the helper cell. In particular, the helper cell expresses DNA from the E2 region of the adenovirus 5 genome and complements deletions in that region in the vector construct.
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