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Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Nissim Benvenisty0
Date of Patent
August 10, 2010
Patent Application Number
11322523
Date Filed
January 3, 2006
Patent Primary Examiner
Patent abstract
Methods are described for mapping a pathway of differentiation of a population of embryonic cells that includes exposing the cells to an exogenous factor and measuring gene expression products that are characteristic of a particular cell type or lineage. Directing differentiation of human embryonic cells relies on dissociated embryoid bodies that are then exposed to one or more exogenous factors to enrich a culture for a particular cell type. The differentiated cells may be used for treating a medical condition in a human. Kits for determining differentiation pathways and screening exogenous factors for their utility in differentiation are provided.
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