Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
March 9, 2010
Patent Application Number
11072980
Date Filed
March 4, 2005
Patent Primary Examiner
Patent abstract
The invention relates to the use of gene therapy in the treatment of aseptic loosening of orthopaedic prostheses and discloses methods of refixing such prostheses without open revision surgery. In particular, it provides adenoviral vectors and prodrugs for simultaneous, separate or sequential use in the destruction of interface tissue allowing subsequent recementing of loose prostheses in a minimally invasive manner.
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