Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 20, 2007
Patent Application Number
10809777
Date Filed
March 24, 2004
Patent Primary Examiner
Patent abstract
The present invention provides methods of detecting an amyloid peptide-related neurological disorder in an individual; and methods for staging an amyloid peptide-related neurological disorder in an individual. The methods involve detecting a level of a calcium-responsive gene product, such as calbindin, in a hippocampal neuron, especially a granule cell of the dentate gyrus. The invention further provides identifying an agent that treats an amyloid peptide-related neurological disorder, as well as agents identified by the methods.
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