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AbbVie Inc.

AbbVie Inc.

AbbVie was formed when Abbott separated into two companies where Abbott focuses on medical products and Abbvie is a research-based biopharmaceutical company. Abbvie was founded in 2013 and is headquartered in North Chicago, IL.

AbbVie drug targets include the following conditions: chronic autoimmune diseases in rheumatology, gastroenterology and dermatology, HIV, oncology, neurological disorders such as Parkinson’s disease and multiple sclerosis, metabolic diseases such as thyroid disease and cystic fibrosis complications.

AbbVie’s best-selling drug Humira is an anti-TNF monoclonal antibody used to treat Crohn’s disease, rheumatoid arthritis, ulcerative colitis, hidradenitis suppurativa, psoriasis, psoriatic arthritis, juvenile idiopathic arthritis, ankylosing spondylitis and uveitis. Humira works in autoimmune diseases which are diseases where the immune system attacks its own tissues and organs. Tumor necrosis factor (TNF) is normally produced by the immune system but in autoimmune diseases the body can produce too much TNF. HUMIRA is a TNF blocker that binds to TNF preventing reducing its damaging effects.

Abbvie’s HIV drug called Kaletra (Aluvia) is recommended by China’s National Health Commission as treatment for the COVID-19 pneumonia caused by the new coronavirus. The company has plans to donate CNY 10 million (about $15 million) worth of the drug to its China branch. The two antiviral components in Kaletra are lopinar and ritonavir which are protease inhibitors designed to block HIV viral replication. It is hypothesized that the drugs could work for the new coronavirus strain 2019-nCoV. Kaletra treatment was given to Wang Guangfa of Peking University First Hospital who contracted the virus with a positive outcome. Kaletra has previously been shown to be effective against another coronavirus, SARS-CoV.

Timeline

2012
AbbVie Inc. was founded.

People

Name
Role
LinkedIn

A. Wojtek

Employee

Aakaash Meduri

Employee

Abasi Ene-Obong Ph.D.

Employee

Abbey Hagen

Employee

Abraham Zavala-Quinones

Employee

Adam Guillemette

Employee

Adam Guillemette

Employee

Aditya Gupta

Employee

aditya koyyalamudi

Employee

Adya Sharma

Employee

Aicha Aissaoui

Employee

Akash Yerukola

Employee

Alain Zogheib

Employee

Alec Preston

Employee

Alexander Anikin

Employee

Alexander Soave

Employee

Alexander Sugg

Employee

Alexandra Yeager

Employee

Ali Siam

Employee

alice stuurman

Employee

AMITH BHARADWAJ

Employee

Amrit Nanda

Employee

Ana Marin Mendoza

Employee

Ana Sablić Skrobo

Employee

Anamaria Mrejeru

Employee

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Further reading

Title
Author
Link
Type
Date

Early Coronavirus Drug Trials Yield Mixed Results

Jason Gale

Web

March 18, 2020

Documentaries, videos and podcasts

Title
Date
Link

Companies

Company
CEO
Location
Products/Services

News

Title
Author
Date
Publisher
Description
AbbVie
June 7, 2021
www.prnewswire.com:443
/PRNewswire/ -- AbbVie (NYSE: ABBV) today announced new data from the Phase 2 CAPTIVATE (PCYC-1142) study investigating IMBRUVICA® (ibrutinib) in combination...

References

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