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List of companies in Flagship Pioneering's investment portfolio

List of companies in Flagship Pioneering's investment portfolio
List of companies in Merit Circle's investment portfolio
List of companies in Almeda Ventures's investment portfolio
List of companies in Paul Mckellar's investment portfolio
Companies in the Direct-to-consumer industry
Companies in the Diagnostic Equipment industry
Companies where
Investors
Name
is
Name
Description
Industry
Official Website
Location
Rubius Therapeutics
Rubius Therapeutics

Rubius Therapeutics is a biotechnology company using stem cells to develop red blood cell cellular therapies.

Biology
Biology
Biomedical engineering
Biomedical engineering
Healthcare
Healthcare
Regenerative medicine
Regenerative medicine
Therapeutics
Therapeutics
Immunotherapy
Immunotherapy
Biotechnology
Biotechnology
Oncology
Oncology
Cancer immunotherapy
Cancer immunotherapy
Technology
Technology
Stem cell technology
Stem cell technology
Biopharmaceutical
Biopharmaceutical
Stem cell
Stem cell
Autoimmune disease
Autoimmune disease
Internal medicine
Internal medicine
Cell therapy
Cell therapy
Cancer
Cancer
Engineering
Engineering
Medicine
Medicine
rubiustx.com
‌
Smithfield, Rhode Island
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
Visterra
Visterra

A company developing antibody-based biological medicines for kidney diseases and other chronic diseases. Visterra was acquired by Otsuka Pharmaceutical in 2018.

Biopharmaceutical
Biopharmaceutical
Healthcare
Healthcare
Autoimmune disease
Autoimmune disease
Biology
Biology
Technology
Technology
Biotechnology
Biotechnology
Therapeutics
Therapeutics
Drug discovery
Drug discovery
visterrainc.com
United States
United States
Waltham, Massachusetts
Waltham, Massachusetts
Cambridge, Massachusetts
Cambridge, Massachusetts
T2 Biosystems
T2 Biosystems

T2 Biosystems is a Lexington, Massachusetts-based company developing diagnostic products targeting sepsis and in vitro diagnostic products intended to target sepsis, hemostasis, bacteria, and lyme disease founded in 2006 by Robin Toft.

Healthcare
Healthcare
Nanotechnology
Nanotechnology
Technology
Technology
Biotechnology
Biotechnology
‌
Nanomedicine
Medical diagnostics
Medical diagnostics
Engineering
Engineering
Biology
Biology
Biomedical engineering
Biomedical engineering
t2biosystems.com
United States
United States
Wilmington, Massachusetts
Wilmington, Massachusetts
Lexington, Massachusetts
Lexington, Massachusetts
Codiak BioSciences
Codiak BioSciences

Codiak Biosciences is a biotechnology company developing exosome therapeutics.

Internal medicine
Internal medicine
Neuroscience
Neuroscience
Engineering
Engineering
Immunotherapy
Immunotherapy
Medicine
Medicine
Healthcare
Healthcare
Stem cell technology
Stem cell technology
Cancer
Cancer
Oncology
Oncology
Alzheimer's disease
Alzheimer's disease
Cancer immunotherapy
Cancer immunotherapy
Cell therapy
Cell therapy
Stem-cell therapy
Stem-cell therapy
Technology
Technology
Stem cell
Stem cell
‌
Synthetic chemistry
Biomedical engineering
Biomedical engineering
Biopharmaceutical
Biopharmaceutical
Biotechnology
Biotechnology
Biology
Biology
Diagnostic tools
Diagnostic tools
‌
Neurodegenerative Disease
codiakbio.com
San Francisco
San Francisco
Woburn, Massachusetts
Woburn, Massachusetts
United States
United States
California
California
Cambridge, Massachusetts
Cambridge, Massachusetts
Editas Medicine
Editas Medicine

Editas Medicine is a genome editing company founded in 2013 that is using CRISPR technology to treat patients with genetically defined diseases.

‌
Synthetic chemistry
Biology
Biology
Induced pluripotent stem cell
Induced pluripotent stem cell
Therapeutics
Therapeutics
RNA-based and RNA-targeted therapeutics
RNA-based and RNA-targeted therapeutics
Tissue engineering
Tissue engineering
Genetic engineering
Genetic engineering
Biomedical engineering
Biomedical engineering
CRISPR/Cas Tools
CRISPR/Cas Tools
Synthetic biology
Synthetic biology
Biotechnology
Biotechnology
Regenerative medicine
Regenerative medicine
‌
Genome editing
Technology
Technology
Healthcare
Healthcare
CRISPR
CRISPR
Pharmaceutical industry
Pharmaceutical industry
Genomics
Genomics
Engineering
Engineering
editasmedicine.com
United States
United States
Boulder, Colorado
Boulder, Colorado
Colorado
Colorado
Cambridge, Massachusetts
Cambridge, Massachusetts
Seres Therapeutics
Seres Therapeutics

Seres Therapeutics is a microbiome therapeutics company that was founded in 2010 and headquartered in Cambridge, Massachusetts.

Microbiology
Microbiology
Biotechnology
Biotechnology
Microbiome
Microbiome
Engineering
Engineering
Biomedical engineering
Biomedical engineering
Therapeutics
Therapeutics
Technology
Technology
Biology
Biology
‌
Pharmabiotics
serestherapeutics.com
Massachusetts
Massachusetts
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
Sigilon Therapeutics
Sigilon Therapeutics

Sigilon Therapeutics is a Cambridge, Massachusetts-based biotechnology company founded by Omid Veiseh.

Biology
Biology
Immunotherapy
Immunotherapy
Cell therapy
Cell therapy
Technology
Technology
Healthcare
Healthcare
Engineering
Engineering
Regenerative medicine
Regenerative medicine
Biomedical engineering
Biomedical engineering
Stem cell technology
Stem cell technology
Tissue engineering
Tissue engineering
Stem cell
Stem cell
Biotechnology
Biotechnology
Speciality chemicals
Speciality chemicals
sigilon.com
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
Joule (company)
Joule (company)

A biotechnology company that specialized in the renewable energy sector. It was located in Bedford, Massachusetts and is no longer in operation.

Biofuel
Biofuel
Biotechnology
Biotechnology
Synthetic biology
Synthetic biology
Clean technology
Clean technology
Technology
Technology
Energy industry
Energy industry
‌
Oil and Gas
Sustainability
Sustainability
Fermentation
Fermentation
Biology
Biology
Alternative fuel
Alternative fuel
jouleunlimited.com
Bedford, Massachusetts
Bedford, Massachusetts
Bedford
Bedford
Agios Pharmaceuticals
Agios Pharmaceuticals

Agios Pharmaceuticals is a public American pharmaceutical company

Pharmaceutical industry
Pharmaceutical industry
Drug discovery
Drug discovery
Biomedical engineering
Biomedical engineering
Enzyme kinetics
Enzyme kinetics
Pharmacokinetics
Pharmacokinetics
Engineering
Engineering
Chemistry
Chemistry
Technology
Technology
Biotechnology
Biotechnology
Healthcare
Healthcare
Immunotherapy
Immunotherapy
Biology
Biology
Drug metabolism
Drug metabolism
agios.com
Cambridge, Massachusetts
Cambridge, Massachusetts
Kaleido Biosciences
Kaleido Biosciences

Kaleido Biosciences is a biotechnology company making discoveries in genetic and metabolic diversity of the human microbiome into treatment and therapies for a wide range of diseases.

Engineering
Engineering
Microbiome
Microbiome
Biomedical engineering
Biomedical engineering
Biopharmaceutical
Biopharmaceutical
Consumer biotechnology
Consumer biotechnology
Technology
Technology
Microbiology
Microbiology
Biotechnology
Biotechnology
Biology
Biology
kaleido.com
Massachusetts
Massachusetts
United States
United States
Bedford, Massachusetts
Bedford, Massachusetts
Lexington, Massachusetts
Lexington, Massachusetts
Acceleron Pharma
Acceleron Pharma

A biopharmaceutical company focused on the discovery, development and commercialization of therapeutics for the treatment of serious and rare diseases

Biotechnology
Biotechnology
Biomedical engineering
Biomedical engineering
Healthcare
Healthcare
Therapeutics
Therapeutics
Technology
Technology
Engineering
Engineering
Biology
Biology
Pharmaceutical industry
Pharmaceutical industry
acceleronpharma.comacceleron.com
Boston
Boston
Cambridge, Massachusetts
Cambridge, Massachusetts
Rahway, New Jersey
Rahway, New Jersey
Syros Pharmaceuticals
Syros Pharmaceuticals

A company focused on mapping and controlling the genes to treat diseases

Life science
Life science
Biomedical engineering
Biomedical engineering
Biology
Biology
Biotechnology
Biotechnology
Engineering
Engineering
Technology
Technology
Enzyme kinetics
Enzyme kinetics
Chemistry
Chemistry
Genetics
Genetics
syros.com
Cambridge, Massachusetts
Cambridge, Massachusetts
United States
United States
Sana Biotechnology
Sana Biotechnology

Sana Biotechnology is a biotechnology company engineering cells to help treat disease.

Engineering
Engineering
Biopharmaceutical
Biopharmaceutical
Synthetic biology
Synthetic biology
Biomedical engineering
Biomedical engineering
Immunotherapy
Immunotherapy
Speciality chemicals
Speciality chemicals
Biology
Biology
‌
Genome editing
Healthcare
Healthcare
Regenerative medicine
Regenerative medicine
Stem cell technology
Stem cell technology
Genomics
Genomics
Technology
Technology
Induced pluripotent stem cell
Induced pluripotent stem cell
Biotechnology
Biotechnology
Cell therapy
Cell therapy
Medicine
Medicine
Stem cell
Stem cell
sana.com
Cambridge, Massachusetts
Cambridge, Massachusetts
South San Francisco, California
South San Francisco, California
Seattle
Seattle
California
California
San Francisco
San Francisco
United States
United States
Indigo
Indigo

Indigo is an agricultural technology company utilizing natural microbiology and digital technologies to improve farmers' profitability, environmental sustainability and consumer health.

Clean technology
Clean technology
Agriculture
Agriculture
Artificial Intelligence (AI)
Artificial Intelligence (AI)
Technology
Technology
Geospatial intelligence
Geospatial intelligence
Sustainable agriculture
Sustainable agriculture
Agritech
Agritech
Agricultural biotechnology
Agricultural biotechnology
Agricultural technology (AgTech)
Agricultural technology (AgTech)
Food technology
Food technology
Biotechnology
Biotechnology
E-agriculture
E-agriculture
Microbiome
Microbiome
Sustainability
Sustainability
Carbon
Carbon
Biology
Biology
indigoag.com
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
Charlestown, Boston
Charlestown, Boston
Boston
Boston
Oasys Water
Oasys Water

Oasys Water was a company that developed water treatment and filtration products.

Environment
Environment
Water industry
Water industry
Energy industry
Energy industry
Water purification
Water purification
Sustainability
Sustainability
‌
Renewables
Industrial
Industrial
Clean technology
Clean technology
Technology
Technology
Cambridge, Massachusetts
Cambridge, Massachusetts
Boston
Boston
Helicos Biosciences
Helicos Biosciences

Helicos Biosciences is a company developing the Helicos® Genetic Analysis System to directly measure RNA, cDNA, and DNA and make them available to the scientific community.

Biology
Biology
Life science
Life science
Technology
Technology
Biotechnology
Biotechnology
helicosbio.com
Cambridge, Massachusetts
Cambridge, Massachusetts
Avedro
Avedro

Avedro is a company that is advancing the field of Corneal Remodeling.

Health technology
Health technology
Medical device
Medical device
Pharmaceutical industry
Pharmaceutical industry
Healthcare
Healthcare
avedro.com
United States
United States
Waltham, Massachusetts
Waltham, Massachusetts
Inari
Inari

Inari is a biotechnology and agricultural technology company

Agriculture
Agriculture
CRISPR/Cas Tools
CRISPR/Cas Tools
Clean technology
Clean technology
Synthetic biology
Synthetic biology
Agricultural biotechnology
Agricultural biotechnology
Biotechnology
Biotechnology
Technology
Technology
Agricultural technology (AgTech)
Agricultural technology (AgTech)
Biology
Biology
inari.com
United States
United States
Belgium
Belgium
West Lafayette, Indiana
West Lafayette, Indiana
Cambridge, Massachusetts
Cambridge, Massachusetts
Zwijnaarde
Zwijnaarde
Black Duck Software
Black Duck Software

Black Duck provides an open source software management and security platform for enterprises.

Software security
Software security
Cybersecurity
Cybersecurity
Technology
Technology
Open-source software
Open-source software
Open source management
Open source management
Software
Software
blackducksoftware.com
Mountain View, Contra Costa County, California
Mountain View, Contra Costa County, California
Burlington, Massachusetts
Burlington, Massachusetts
Mountain View, California
Mountain View, California
United States
United States
Foghorn Therapeutics
Foghorn Therapeutics

Foghorn Therapeutics is a Cambridge, Massachusetts-based company developing gene-specific therapies.

Biopharmaceutical
Biopharmaceutical
Biomedical engineering
Biomedical engineering
Engineering
Engineering
Biology
Biology
Consumer biotechnology
Consumer biotechnology
Technology
Technology
Healthcare
Healthcare
Therapeutics
Therapeutics
Oncology
Oncology
Biotechnology
Biotechnology
Cancer
Cancer
‌
Synthetic chemistry
Internal medicine
Internal medicine
Medicine
Medicine
foghorntx.com
Cambridge, Massachusetts
Cambridge, Massachusetts
United States
United States
Kovio
Kovio

Kovio was a technology company specializing in the manufacture of electronic devices based on printed silicon electronics and thin film technologies.

Semiconductor
Semiconductor
kovio.com
San Jose, California
San Jose, California
Inari
Inari

INARI provides technology software for insurers, reinsurers, MGAs and Lloyd's syndicates on a cloud-based blockchain platform.

Insurance
Insurance
Insurance Technology
Insurance Technology
Financial technology
Financial technology
Software as a service (SaaS)
Software as a service (SaaS)
‌
Reinsurance
Productivity
Productivity
Technology
Technology
Finance
Finance
inari.io
Boston
Boston
Barcelona
Barcelona
Novomer
Novomer

Novomer is a Waltham, Massachusetts-based company founded in 2004 by Scott D. Allen.

Chemical Manufacturing
Chemical Manufacturing
Polymer
Polymer
Carbon Utilization
Carbon Utilization
‌
Green chemistry
Plastics industry
Plastics industry
Carbon capture and storage
Carbon capture and storage
novomer.com
Waltham, Massachusetts
Waltham, Massachusetts
BG Medicine
BG Medicine

BG Medicine is a company developing diagnostic products for heart failure and related disorders.

Healthcare
Healthcare
Biology
Biology
Technology
Technology
Genetics
Genetics
Hospital
Hospital
Biotechnology
Biotechnology
Therapeutics
Therapeutics
bg-medicine.com
Foxborough, Massachusetts
Foxborough, Massachusetts
Massachusetts
Massachusetts
Waltham, Massachusetts
Waltham, Massachusetts
Axcella
Axcella

Axcella is a clinical-stage biotechnology company.

Technology
Technology
Drug metabolism
Drug metabolism
Biology
Biology
Enzyme kinetics
Enzyme kinetics
Biopharmaceutical
Biopharmaceutical
Chemistry
Chemistry
Life science
Life science
Pharmacokinetics
Pharmacokinetics
Biotechnology
Biotechnology
Consumer biotechnology
Consumer biotechnology
Healthcare
Healthcare
axcellahealth.com
Cambridge, Massachusetts
Cambridge, Massachusetts
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