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US Patent 11903966 Intracellular genomic transplant and methods of therapy

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 US Patent 11903966 Intracellular genomic transplant and methods of therapy

Article

Patent abstract

Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.

Infobox
Is a
Patent
Patent
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
119039660
Patent Inventor Names
Beau Webber0
Branden Moriarity0
Douglas C. Palmer0
Modassir Choudhry0
Nicholas P. Restifo0
Steven A. Rosenberg0
Date of Patent
February 20, 2024
0
Patent Application Number
161808670
Date Filed
November 5, 2018
0
Patent Citations
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US Patent 7265209 CE7-specific chimeric T cell receptor
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US Patent 7446190 Nucleic acids encoding chimeric T cell receptors
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US Patent 7608410 Method of improving T cell receptors
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US Patent 7619057 MHC class II restricted T cell epitopes from the cancer antigen, NY ESO-1
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US Patent 7723111 Activated dual specificity lymphocytes and their methods of use
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US Patent 7741465 Chimeric receptor genes and cells transformed therewith
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US Patent 7763718 Soluble T cell receptors
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US Patent 7868158 Modulation of cytokine signaling regulators and applications for immunotherapy
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US Patent 8124408 Preparation of inactivated artificial antigen presenting cells and their use in cell therapies
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US Patent 8211422 Chimeric receptor genes and cells transformed therewith
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US Patent 8354516 Polypeptide producing cells
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US Patent 8367804 High affinity NY-ESO T cell receptors
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US Patent 8389282 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes
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US Patent 8399645 Chimeric receptors with 4-1BB stimulatory signaling domain
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US Patent 8486694 Generation of antigen specific T cells
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US Patent 8541204 Polypeptide producing cells
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US Patent 8546553 Prokaryotic RNAi-like system and methods of use
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US Patent 8697359 CRISPR-Cas systems and methods for altering expression of gene products
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US Patent 8754046 MHC class II restricted T cell epitopes from the cancer anitgen, NY ESO-1
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US Patent 8771945 CRISPR-Cas systems and methods for altering expression of gene products
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US Patent 8795965 CRISPR-Cas component systems, methods and compositions for sequence manipulation
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US Patent 8865406 Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
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US Patent 8871445 CRISPR-Cas component systems, methods and compositions for sequence manipulation
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US Patent 8889356 CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
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US Patent 8889365 Methods and kit for detecting breast cancer
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US Patent 8889418 Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
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US Patent 8895308 Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
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US Patent 8906616 Engineering of systems, methods and optimized guide compositions for sequence manipulation
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US Patent 8921332 Chromosomal modification involving the induction of double-stranded DNA cleavage and homologous recombination at the cleavage site
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US Patent 8932814 CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
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US Patent 8945839 CRISPR-Cas systems and methods for altering expression of gene products
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US Patent 8993233 Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
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US Patent 8999641 Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
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US Patent 9023649 RNA-guided human genome engineering
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US Patent 9074185 Adoptive cell therapy with young T cells
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US Patent 9131589 Extreme ultraviolet light generation apparatus and control method for laser apparatus in extreme ultraviolet light generation system
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US Patent 9234213 Compositions and methods directed to CRISPR/Cas genomic engineering systems
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US Patent 9260723 RNA-guided human genome engineering
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US Patent 9260752 Compositions and methods of nucleic acid-targeting nucleic acids
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US Patent 9362208 Packaged semiconductor components having substantially rigid support members and methods of packaging semiconductor components
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US Patent 9393257 TALEN-based gene correction
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US Patent 9404098 Method for cleaving a target RNA using a Cas6 polypeptide
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US Patent 9410198 Compostions and methods of nucleic acid-targeting nucleic acids
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US Patent 9458439 Chromosomal modification involving the induction of double-stranded DNA cleavage and homologous recombination at the cleavage site
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US Patent 9570114 Laminated film-packed hard disk drive for hermetic sealing
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US Patent 10550405 Rational polyploid adeno-associated virus vectors and methods of making and using the same
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US Patent 10570418 Methods and compositions for RNA-directed target DNA modification
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US Patent 10912797 Tumor infiltrating lymphocytes and methods of therapy
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US Patent 10975149 Inhibition of cytokine-induced SH2 protein in NK cells
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US Patent 7070995 CE7-specific redirected immune cells
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Patent Primary Examiner
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Arthur S Leonard
0

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