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US Patent 8889418 Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation

Overview Structured Data Issues Contributors

Is a

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Fei Ran0

Feng Zhang0

Date of Patent

November 18, 2014

Patent Application Number

14293674

Date Filed

June 2, 2014

Patent Citations Received

US Patent 12123032 CRISPR enzyme mutations reducing off-target effects

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US Patent 12110545 Methods of assessing nuclease cleavage

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US Patent 12116619 CRISPR mediated in vivo modeling and genetic screening of tumor growth and metastasis

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US Patent 12121524 DNA-PK inhibitors

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US Patent 12123012 Methods and compositions for nucleic acid and protein payload delivery

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US Patent 12123015 Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

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US Patent 11661590 Programmable CAS9-recombinase fusion proteins and uses thereof

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US Patent 11667911 Use of exonucleases to improve CRISPR/CAS-mediated genome editing

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