Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Bent Karsten Jakobsen0
Jonathan Michael Boulter0
Peter Eamon Molloy0
Steven Mark Dunn0
Yi Li0
Date of Patent
February 5, 2013
0Patent Application Number
131760900
Date Filed
July 5, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides T cell receptors (TCRs) having the property of binding to SLLMWITQC-HLA-A*0201, the SLLMWITQC SEQ ID NO:126 peptide being derived from the NY-ESO-1 protein which is expressed by a range of tumour cells. The TCRs have a KD for the said peptide-HLA complex of less than or equal to 1 μM and/or have an off-rate (koff) of 1×10−3 S−1 or slower.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
