Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Nicholas D. Huntington0
Jeff Babon0
Sandra E. Nicholson0
Tatiana Kolesnik0
Date of Patent
April 13, 2021
Patent Application Number
16060996
Date Filed
December 16, 2016
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells. The invention further relates to methods for identifying a CIS inhibitor, and for determining a likelihood of cancer response to treatment with CIS inhibition.
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