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US Patent 10975149 Inhibition of cytokine-induced SH2 protein in NK cells

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US Patent 11925664 Intracellular genomic transplant and methods of therapy

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US Patent 11903966 Intracellular genomic transplant and methods of therapy

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US Patent 11883432 Chimeric antigen receptor system with adaptable receptor specificity

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Patent abstract

The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells. The invention further relates to methods for identifying a CIS inhibitor, and for determining a likelihood of cancer response to treatment with CIS inhibition.

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Patent Inventor Names

Jeff Babon0

Nicholas D. Huntington0

Sandra E. Nicholson0

Tatiana Kolesnik0

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US Patent 11661459 Artificial cell death polypeptide for chimeric antigen receptor and uses thereof

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Official Website

https://pdfpiw.uspto.gov/.piw?Docid=10975149

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US Patent 11642374 Intracellular genomic transplant and methods of therapy

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US Patent 11266692 Intracellular genomic transplant and methods of therapy

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US Patent 11583556 Modified cells and methods of therapy

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Website URL

https://pdfpiw.uspto.gov/.piw?Docid=10975149

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US Patent 11266692 Intracellular genomic transplant and methods of therapy

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US Patent 10975149 Inhibition of cytokine-induced SH2 protein in NK cells

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Is a

Patent jurisdiction

United States Patent and Trademark Office

Patent number

10975149

Date of patent

April 13, 2021

Patent application number

16060996

Date Filed

December 16, 2016

Patent primary examiner

Daniel C Gamett

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