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List of companies in Third Rock Ventures's investment portfolio

List of companies in Third Rock Ventures's investment portfolio
List of companies in HarbourVest Partners's investment portfolio
List of companies in Concrete Rose Capital's investment portfolio
List of companies in Octagon Capital Partners's investment portfolio
List of Samson Rope Technologies patents
CEOs of fuel companies
Companies where
Investors
Name
is
Name
Description
Industry
Official Website
Location
Jounce Therapeutics
Jounce Therapeutics

Jounce Therapeutics is an immunotherapy company developing therapies to cancer founded in 2013 by James P. Allison, Drew Pardoll, Louis M. Weiner, Padmanee Sharma, Robert D. Schreiber and Thomas F. Gajewski.

Oncology
Oncology
Medicine
Medicine
Engineering
Engineering
Cancer immunotherapy
Cancer immunotherapy
Therapy
Therapy
Biology
Biology
Immunotherapy
Immunotherapy
Therapeutics
Therapeutics
Biomedical engineering
Biomedical engineering
Biopharmaceutical
Biopharmaceutical
Cancer
Cancer
Healthcare
Healthcare
Enterprise software
Enterprise software
Software
Software
Technology
Technology
Internal medicine
Internal medicine
Biotechnology
Biotechnology
jouncetx.com
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
Kala Pharmaceuticals
Kala Pharmaceuticals

A biopharmaceutical company that develops nanotherapeutic treatments for ocular diseases and other eye related conditions

Biopharmaceutical
Biopharmaceutical
Technology
Technology
Biology
Biology
Drug delivery
Drug delivery
Engineering
Engineering
Healthcare
Healthcare
Biotechnology
Biotechnology
Therapy
Therapy
Biomedical engineering
Biomedical engineering
Therapeutics
Therapeutics
kalarx.com
Watertown, Massachusetts
Watertown, Massachusetts
Arlington, Massachusetts
Arlington, Massachusetts
United States
United States
Waltham, Massachusetts
Waltham, Massachusetts
Decibel Therapeutics
Decibel Therapeutics

Decibel Therapeutics conducts inner ear research to deliver medicines for hearing and balance.

Engineering
Engineering
Drug discovery
Drug discovery
Biology
Biology
Technology
Technology
Biomedical engineering
Biomedical engineering
Therapeutics
Therapeutics
‌
Synthetic chemistry
Biotechnology
Biotechnology
decibeltx.com
United States
United States
Boston
Boston
Voyager Therapeutics
Voyager Therapeutics

Voyager Therapeutics is a biotechnology company founded in 2014 that is headquartered in Cambridge, Massachusetts developing gene therapies to treat neurological disorders.

Technology
Technology
Genetic engineering
Genetic engineering
Biomedical engineering
Biomedical engineering
Medicine
Medicine
Regenerative medicine
Regenerative medicine
Biotechnology
Biotechnology
Engineering
Engineering
Alzheimer's disease
Alzheimer's disease
‌
Neurodegenerative Disease
Healthcare
Healthcare
Neuroscience
Neuroscience
Biology
Biology
‌
Neurobiology
Parkinson's disease
Parkinson's disease
Biopharmaceutical
Biopharmaceutical
Consumer biotechnology
Consumer biotechnology
Therapeutics
Therapeutics
Gene therapy
Gene therapy
voyagertherapeutics.com
Cambridge, Massachusetts
Cambridge, Massachusetts
United States
United States
Cambridge, Cambridgeshire
Cambridge, Cambridgeshire
Editas Medicine
Editas Medicine

Editas Medicine is a genome editing company founded in 2013 that is using CRISPR technology to treat patients with genetically defined diseases.

‌
Synthetic chemistry
Biology
Biology
Induced pluripotent stem cell
Induced pluripotent stem cell
Therapeutics
Therapeutics
RNA-based and RNA-targeted therapeutics
RNA-based and RNA-targeted therapeutics
Tissue engineering
Tissue engineering
Genetic engineering
Genetic engineering
Biomedical engineering
Biomedical engineering
CRISPR/Cas Tools
CRISPR/Cas Tools
Synthetic biology
Synthetic biology
Biotechnology
Biotechnology
Regenerative medicine
Regenerative medicine
‌
Genome editing
Technology
Technology
Healthcare
Healthcare
CRISPR
CRISPR
Pharmaceutical industry
Pharmaceutical industry
Genomics
Genomics
Engineering
Engineering
editasmedicine.com
United States
United States
Boulder, Colorado
Boulder, Colorado
Colorado
Colorado
Cambridge, Massachusetts
Cambridge, Massachusetts
Bluebird Bio
Bluebird Bio

A company developing gene therapies for the treatment of genetic diseases and cancer.

Biotechnology
Biotechnology
Technology
Technology
Biomedical engineering
Biomedical engineering
Epigenetics
Epigenetics
RNA-based and RNA-targeted therapeutics
RNA-based and RNA-targeted therapeutics
Genetic engineering
Genetic engineering
Healthcare
Healthcare
Cell therapy
Cell therapy
Biology
Biology
‌
Rare disease
Tissue engineering
Tissue engineering
Genomics
Genomics
T cell
T cell
‌
CAR T-Cell therapy
Regenerative medicine
Regenerative medicine
‌
Genome editing
Drug discovery
Drug discovery
Engineering
Engineering
Gene therapy
Gene therapy
Immunotherapy
Immunotherapy
bluebirdbio.com
Somerville, Massachusetts
Somerville, Massachusetts
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
SAGE Therapeutics
SAGE Therapeutics

Sage Therapeutics is a biopharmaceutical company founded by Douglas Covey and Steven Paul in 2010 and headquartered in Cambridge, Massachusetts focused on the discovery and development of medicines to address central nervous system disorders.

Biomedical engineering
Biomedical engineering
Technology
Technology
Biotechnology
Biotechnology
Biology
Biology
Engineering
Engineering
Neuroscience
Neuroscience
Healthcare
Healthcare
Pharmaceutical industry
Pharmaceutical industry
‌
Digital therapeutics
Therapeutics
Therapeutics
Biopharmaceutical
Biopharmaceutical
sagerx.com
Raleigh, North Carolina
Raleigh, North Carolina
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
CytomX Therapeutics
CytomX Therapeutics

A biotechnology company that develops Probodies, proteolytically-activated antibodies to treat cancer.

Technology
Technology
Immunology
Immunology
Cancer
Cancer
Therapeutics
Therapeutics
Biopharmaceutical
Biopharmaceutical
Engineering
Engineering
Internal medicine
Internal medicine
Therapy
Therapy
Biomedical engineering
Biomedical engineering
Immunotherapy
Immunotherapy
Biology
Biology
Medicine
Medicine
T cell
T cell
Oncology
Oncology
Healthcare
Healthcare
Biotechnology
Biotechnology
cytomx.com
San Francisco
San Francisco
South San Francisco, California
South San Francisco, California
United States
United States
Insitro
Insitro

A bioinformatics company in San Francisco building data collection methods and databases that will enable machine learning algorithms in healthcare. It was founded in 2018.

Cancer immunotherapy
Cancer immunotherapy
Synthetic biology
Synthetic biology
Life science
Life science
Biology
Biology
Cancer
Cancer
Biotechnology
Biotechnology
Oncology
Oncology
Machine learning
Machine learning
Therapeutics
Therapeutics
Immunotherapy
Immunotherapy
Engineering
Engineering
Artificial Intelligence (AI)
Artificial Intelligence (AI)
Alzheimer's disease
Alzheimer's disease
Drug discovery
Drug discovery
Diabetes mellitus
Diabetes mellitus
Biomedical engineering
Biomedical engineering
Internal medicine
Internal medicine
Technology
Technology
insitro.com
San Francisco
San Francisco
South San Francisco, California
South San Francisco, California
United States
United States
Magenta Therapeutics
Magenta Therapeutics

Magenta Therapeutics is a biotechnology company using stem cells to develop cellular therapies for immune and blood-based diseases.

Stem cell
Stem cell
Biomedical engineering
Biomedical engineering
Healthcare
Healthcare
Immunotherapy
Immunotherapy
Stem-cell therapy
Stem-cell therapy
Biotechnology
Biotechnology
Biology
Biology
Technology
Technology
Stem cell technology
Stem cell technology
Regenerative medicine
Regenerative medicine
Cell therapy
Cell therapy
Engineering
Engineering
Drug discovery
Drug discovery
magentatx.com
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
Foundation Medicine
Foundation Medicine

Foundation Medicine is a Cambridge, Massachusetts-based pharmaceutical company developing diagnostic and treatment solutions for cancer care founded in 2010 by Alexis Borisy.

Medicine
Medicine
Biotechnology
Biotechnology
Biology
Biology
Internal medicine
Internal medicine
Diagnosis
Diagnosis
Technology
Technology
Healthcare
Healthcare
Engineering
Engineering
Medical diagnostics
Medical diagnostics
Biomedical engineering
Biomedical engineering
Oncology
Oncology
Cancer
Cancer
Biopharmaceutical
Biopharmaceutical
Genomics
Genomics
foundationmedicine.com
Cambridge, Massachusetts
Cambridge, Massachusetts
United States
United States
Seventh Sense Biosystems
Seventh Sense Biosystems

A biotechnology company developing blood sampling and testing devices. It was founded in 2008 and is located in Medford, Massachusetts.

Biotechnology
Biotechnology
Medical device
Medical device
Healthcare
Healthcare
Health technology
Health technology
Engineering
Engineering
Technology
Technology
Biomedical engineering
Biomedical engineering
Biology
Biology
7sbio.com
Medford, Massachusetts
Medford, Massachusetts
Agios Pharmaceuticals
Agios Pharmaceuticals

Agios Pharmaceuticals is a public American pharmaceutical company

Pharmaceutical industry
Pharmaceutical industry
Drug discovery
Drug discovery
Biomedical engineering
Biomedical engineering
Enzyme kinetics
Enzyme kinetics
Pharmacokinetics
Pharmacokinetics
Engineering
Engineering
Chemistry
Chemistry
Technology
Technology
Biotechnology
Biotechnology
Healthcare
Healthcare
Immunotherapy
Immunotherapy
Biology
Biology
Drug metabolism
Drug metabolism
agios.com
Cambridge, Massachusetts
Cambridge, Massachusetts
Relay Therapeutics
Relay Therapeutics

Relay Therapeutics is a Cambridge, Massachusetts-based developer of an allosteric drug-discover platform that is intended to apply computational techniques to protein motion.

Technology
Technology
Biotechnology
Biotechnology
Therapeutics
Therapeutics
Biomedical engineering
Biomedical engineering
Biology
Biology
Engineering
Engineering
relaytx.com
Cambridge, Massachusetts
Cambridge, Massachusetts
United States
United States
Rhythm Pharmaceuticals
Rhythm Pharmaceuticals

A biopharmaceutical company developing and commercializing peptide therapeutics to treat rare genetic disorders of obesity

Biotechnology
Biotechnology
Technology
Technology
Biology
Biology
Therapeutics
Therapeutics
Consumer biotechnology
Consumer biotechnology
Engineering
Engineering
RNA-based and RNA-targeted therapeutics
RNA-based and RNA-targeted therapeutics
Biomedical engineering
Biomedical engineering
Medical diagnostics
Medical diagnostics
rhythmtx.com
United States
United States
Boston
Boston
Blueprint Medicines
Blueprint Medicines

Blueprint Medicines is a biotechnology company that is working to improve human health.

‌
Synthetic chemistry
Diagnosis
Diagnosis
Technology
Technology
Engineering
Engineering
Biology
Biology
Biopharmaceutical
Biopharmaceutical
Life science
Life science
Biomedical engineering
Biomedical engineering
Healthcare
Healthcare
Biotechnology
Biotechnology
blueprintmedicines.com
Cambridge, Cambridgeshire
Cambridge, Cambridgeshire
Switzerland
Switzerland
Zug
Zug
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
San Diego
San Diego
Goldfinch Biopharma
Goldfinch Biopharma

Goldfinch Biopharma is a Cambridge, Massachusetts-based therapeutics company focused on discovering and developing precision therapies for patients with kidney disease.

Health technology
Health technology
Therapeutics
Therapeutics
Healthcare
Healthcare
Medical device
Medical device
goldfinchbio.com/#home
Cambridge, Massachusetts
Cambridge, Massachusetts
Constellation Pharmaceuticals
Constellation Pharmaceuticals

A biopharmaceutical company dedicated to the development of novel therapeutics in the field of Epigenetics

Biomedical engineering
Biomedical engineering
Technology
Technology
Biopharmaceutical
Biopharmaceutical
Biotechnology
Biotechnology
Engineering
Engineering
Biology
Biology
constellationpharma.com
Cambridge, Cambridgeshire
Cambridge, Cambridgeshire
Boston
Boston
Boston, Massachusetts, United States
Boston, Massachusetts, United States
Planegg
Planegg
Cambridge, Massachusetts
Cambridge, Massachusetts
Nurix
Nurix

A company developing protein homeostasis therapies for oncology, immunology, and inflammation cases

Technology
Technology
Cancer
Cancer
Internal medicine
Internal medicine
Therapeutics
Therapeutics
Biology
Biology
Medicine
Medicine
Engineering
Engineering
Oncology
Oncology
Healthcare
Healthcare
Biotechnology
Biotechnology
Biomedical engineering
Biomedical engineering
nurix-inc.comnurixtx.com
San Francisco
San Francisco
MyoKardia
MyoKardia

MyoKardia is a company developing targeted therapies for cardiocavscular diseases founded in 2012 by Leslie Leinwand.

Biotechnology
Biotechnology
Cardiology
Cardiology
‌
Rare disease
Healthcare
Healthcare
Pharmaceutical industry
Pharmaceutical industry
Cardiovascular disease
Cardiovascular disease
Medicine
Medicine
Internal medicine
Internal medicine
Biopharmaceutical
Biopharmaceutical
Biology
Biology
Technology
Technology
myokardia.com
Brisbane, California
Brisbane, California
United States
United States
San Francisco
San Francisco
South San Francisco, California
South San Francisco, California
New York
New York
Maze Therapeutics
Maze Therapeutics

Maze Therapeutics is a San Francisco-based biotechnology company developing genetics-based therapeutics

Technology
Technology
Clean technology
Clean technology
Medicine
Medicine
Healthcare
Healthcare
Oncology
Oncology
Health technology
Health technology
Biopharmaceutical
Biopharmaceutical
Genetics
Genetics
Biomedical engineering
Biomedical engineering
Consumer biotechnology
Consumer biotechnology
Internal medicine
Internal medicine
Genealogy
Genealogy
Biotechnology
Biotechnology
Engineering
Engineering
Synthetic biology
Synthetic biology
Biology
Biology
mazetx.com
South San Francisco, California
South San Francisco, California
Casma Therapeutics
Casma Therapeutics

Casma Therapeutics is a company that has a research community and uses its understanding of research to develop novel therapeutics to capture disease causing targets.

‌
Synthetic chemistry
Therapeutics
Therapeutics
Technology
Technology
Engineering
Engineering
Biology
Biology
Healthcare
Healthcare
Biomedical engineering
Biomedical engineering
Biotechnology
Biotechnology
casmatx.com
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
Asher Biotherapeutics
Asher Biotherapeutics

A biotechnology company offering precision immunotherapy cancer treatments.

Oncology
Oncology
Immunotherapy
Immunotherapy
Biology
Biology
Engineering
Engineering
Cancer immunotherapy
Cancer immunotherapy
Biopharmaceutical
Biopharmaceutical
Biomedical engineering
Biomedical engineering
Biotechnology
Biotechnology
Technology
Technology
asherbio.com
San Francisco
San Francisco
United States
United States
South San Francisco, California
South San Francisco, California
California
California
Global Blood Therapeutics
Global Blood Therapeutics

A biopharmaceutical company developing treatments for sickle cell disease

Biomedical engineering
Biomedical engineering
‌
Synthetic chemistry
Technology
Technology
Engineering
Engineering
Biology
Biology
Biotechnology
Biotechnology
gbt.comglobalbloodtx.com
London
London
Berlin
Berlin
United States
United States
South San Francisco, California
South San Francisco, California
Paris
Paris
Baar, Switzerland
Baar, Switzerland
Celsius Therapeutics
Celsius Therapeutics

Celsius Therapeutics is a company with a community of scientists, computational biologists, technologists and clinicians.

Single-cell analysis
Single-cell analysis
Artificial Intelligence (AI)
Artificial Intelligence (AI)
Engineering
Engineering
Technology
Technology
Drug discovery
Drug discovery
RNA
RNA
Biology
Biology
Therapeutics
Therapeutics
Cell biology
Cell biology
Healthcare
Healthcare
Biomedical engineering
Biomedical engineering
Biotechnology
Biotechnology
Genetics
Genetics
celsiustx.com
Cambridge, Massachusetts
Cambridge, Massachusetts
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