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Sarepta Therapeutics

Sarepta Therapeutics

Sarepta Therapeutics is a biopharmaceutical company founded by Marwan Fawaz in 1980 and headquartered in Cambridge, Massachusetts developing precision genetic medicines for the treatment of rare neuromuscular diseases.

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What is Sarepta Therapeutics?

Serepta Therepeutics, formerly AVI BioPharma, is a biotechnology company that is headquartered in Cambridge, Massachusetts, and was founded in 1980 by Marwan Fawaz. The company is developing gene therapies and medicines for the treatment of neuromuscular diseases such as Duchenne Muscular Dystrophy (DMD), Limb-Girdle Muscular Dystrophy (LGMD), and Charcot-Marie-Tooth (CMT). Serepta Therapeutics creates their gene therapies and medicines using multiple therapeutic approaches which include RNA, gene therapy, and gene editing.

Partners
  • Genethon
  • Murdoch University
  • University of Western Australia

The company has worked with phosphorodiamidate morpholino oligomer chemistries in order to provide therapies for muscular dystrophy. The PMOs that the company works with are synthetic molecules that are modeled after the natural framework of RNA, and has the nucleic acid bases found in RNA.

They are able to hide specific exons, or skip their location if they are missing in order to provide a proper connection and create a functional dystrophin protein.

Timeline

Funding Rounds

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Products

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Acquisitions

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SBIR/STTR Awards

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Patents

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Further Resources

Title
Author
Link
Type
Date

Sarepta Therapeutics enters manufacturing partnership for DMD treatment

Maggie Lynch

https://www.biopharma-reporter.com/Article/2018/10/17/Sarepta-Therapeutics-enters-manufacturing-partnership-for-DMD-treatment

Web

Sarepta Therapeutics shares soar 50% on positive preliminary results for muscular dystrophy gene therapy

Angelica LaVito

https://www.cnbc.com/2018/06/19/sarepta-therapeutics-shares-soar-on-preliminary-gene-therapy-data.html

News

References

sarepta.com
Is a
Company
Company
Organization
Organization

Company attributes

Industry
Biopharmaceutical
Biopharmaceutical
Pharmaceutical industry
Pharmaceutical industry
Therapeutics
Therapeutics
Gene therapy
Gene therapy
Genetic engineering
Genetic engineering
Healthcare
Healthcare
Drug discovery
Drug discovery
...
Location
Andover, Massachusetts
Andover, Massachusetts
United States
United States
Cambridge, Massachusetts
Cambridge, Massachusetts
-1
Corvallis, Oregon
Corvallis, Oregon
North Carolina
North Carolina
CEO
‌
Douglas S. Ingram
-1
Founder
Marwan Fawaz
Marwan Fawaz
-1
Pitchbook URL
pitchbook.com/profiles.../41120-20
Legal Name
Sarepta Therapeutics, Inc.-1
Legal classification
Public company
Public company
-1
Date Incorporated
1980
Number of Employees (Ranges)
501 – 1,000
Number of Employees
840-1
Full Address
215 First Street Cambridge, MA 02142-1
CIK Number
873,303-1
Place of Incorporation
Massachusetts
Massachusetts
DUNS Number
121653406
IRS Number
930,797,222-1
Founded Date
1980
Email Address
medinfoe@sarepta.com
advocacy@sarepta.com-1
Phone Number
+441214680917
+16172744000-1
Total Funding Amount (USD)
430,499,960
Latest Funding Round Date
February 2020
Competitors
Horizon Pharma
Horizon Pharma
Avidity Biosciences
Avidity Biosciences
Stock Symbol
SRPT-1
Exchange
Nasdaq
Nasdaq
Board of Directors
‌
Kathryn Boor
-1
‌
Claude Nicaise
-1
‌
Stephen L. Mayo
-1
‌
Douglas S. Ingram
-1
‌
Hans Wigzell
-1
CFO
‌
Ian M. Estepan
-1
NAICS Code
325,412-1
Patents Assigned (Count)
84
Legal Entity Identifier
549300IKDPIED8J8IG21-1
Wellfound ID
sarepta-therapeutics
Technologies Used
CRISPR
CRISPR

Other attributes

Company Operating Status
Active
Contact Page URL
sarepta.com/about-us/contact-us
Country
United States
United States
-1
Headquarters
Cambridge, Massachusetts
Cambridge, Massachusetts
-1
Previous Name
ANTIVIRALS INC-1
AVI BIOPHARMA INC-1
SIC Code
2,834-1
Ticker Symbol
SRPT-1
Wikidata ID
Q15109846

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