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Recursion Pharmaceuticals

Recursion Pharmaceuticals

A biotechnology and data science company based in Salt Lake City, Utah, founded in 2013, that combines biology with artificial intelligence for drug discovery. Using human cell models of diseases, Recursion captures microscopic images to build biological datasets and computational techniques identify disease-associated biological changes.

For diseases that can be modeled at the cellular level, Recursion uses automation in a massively parallel system to find potential treatments for disease. The initial focus was on repurposing existing drugs to treat rare diseases and has broadened to probe data for markers of inflammation, infectious disease and immunology. Recursion is using its technology to build a map of human cellular biology to increase the pace of discovering new treatments for patients.

Neural networks and other computational techniques will be used to identify changes in thousands of cellular and subcellular features associated with various biological perturbations. This approach, termed phenomics, is the large scale study of phenotypes, the study of how variations in traits are related to genetic and environmental factors. Dr. Yoshua Bengio, a pioneer of deep learning is advising on their AI strategy.

In 2018, an investigational new drug (IND) called REC-994 discovered by Recursion was FDA approved for clinical trials for treatment of cerebral cavernous malformation (CCM). CCM is a genetic disorder characterised by collections of enlarged and irregularly structured small blood vessels in the brain which alter blood flow and lead to symptoms like seizures, vision loss, hearing loss, paralysis, neurologic deficits and hemorrhagic stroke.

Recursion received funding from the Bill and Melinda Gates Foundation in spring 2018 to use its technology to discover new drugs to treat malaria.

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Anne Carpenter

Advisor

Bart Robertson

Investor

Becca Parker

Employee

Ben Sukow

Employee

Blake Borgeson

Founder

brant corenson

Investor

Brian Bargh

Employee

Bril Flint

Investor

Britt McPartland

Employee

Brock Metcalf

Investor

Cedric St-Jean

Employee

Chadwick Davis

Employee

Chris Gibson

Founder

Christopher Johnson

Employee

Craig Dos Santos

Investor

CTAN - Central Texas Angel Network

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Dan Graham

Investor

David Compton

Employee

Dean Li

Founder

Deena Kalai

Investor

Gary Rieschel

Investor

Gerald Lema

Investor

ian quigley

Employee

J.D. White

Employee

J.R. Kraft

Investor

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