EpiBone is a biotechnology company headquartered in New York City, New York that was founded in 2013 by Nina Tandon, Sarindr Bhumiratana, Gordana Vunjak-Novakovic, and Sidney Eisig. CEO and Co-Founder Nina Tandon worked on heart regeneration for her PhD, worked at McKinsey management consultancy and has an MBA.
EpiBone uses a biomedical engineering process that includes 3D printing to create individualized bone grafts using a patients own mesenchymal stem cells grown in the company's custom built bioreactor. The process involves a CT scan to determine the exact size and shape of a needed bone. A precise, personalized scaffold is created. The patient’s stem cells are cultured so that they start becoming bone cells and are placed on the scaffold and remodel into a personalized bone graft that can be implanted.
Phase 1 and 2 clinical trial Investigational New Drug (IND) clearance was granted by the FDA in 2019 for their product EpiBone-Craniomaxillofacial (EB-CMF) as a treatment for ramus continuity defects in the mandible. The product is anatomically correct and manufactured from a patient’s own adipose derived stem cells.
On June 12, 2014 EpiBone received an undisclosed amount of funding in the form of a grant from the Partnership Fund for New York City and Breakout Labs.
On October 1, 2016 EpiBone received a convertible note worth $560 thousand from Plum Alley.
EpiBone, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted its Investigational New Drug (IND) clearance to proceed with a Phase 1/2 clinical trial of its lead bone product EpiBone-Craniomaxillofacial (EB-CMF), as a potential treatment for ramus continuity defects in the mandible.
EpiBone was founded by Nina Tandon.
Co-Founder & Chief Scientific Advisor
Co-Founder & CEO
Co-Founder & CEO
Co-Founder & Chief Clinical Advisor
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- Cluster: BiotechnologyA cluster of topics related to biotechnology.
- Cluster: Stem cell technologyTechnology used for isolating, generating, growing and controlling the differentiation of stem cells into specialized cells and the application of stem cell technology for medical and non-medical purposes such as producing meat through cellular agriculture.
- Breakout LabsBreakout Labs is a grant making body of the Thiel Foundation supporting the commercialization of scientific products and services located in San Francisco, California.
- BiotechnologyBiotechnology can refer to the application of science and technology to living organisms or the use of living organisms, their parts, products or models thereof to solve a problem, produce knowledge or produce goods and services. Biotechnology may involve the alteration of living or non-living materials.
- Regenerative medicineBranch of research dealing with the process of replacing, engineering, or regenerating biological units to (re-)establish normal function