Abraxis BioScience

Abraxis BioScience

A Biopharmaceutical company based in Los Angeles and founded in 2007 that develops therapeutics and technologies using nanotechnology for cancer and other critical illnesses.

Abraxis was acquired by Celgene in 2010. Abraxane is the brand name for the nanoparticle chemotherapeutic compound developed by Abraxis using its proprietary tumor targeting nanoparticle albumin-bound (nab) technology to treat metastatic breast cancer.

In 2005 Abraxis became the first nanodrug approved by the FDA. Generic forms of this drug are called Nab-paclitaxel and along with breast cancer the chemotherapy drug is also used to treat pancreatic cancer and non small cell lung cancer.

Paclitaxel inhibits cell mitosis which prevents cells from multiplying but its hydrophobic nature meant that toxic solvents were needed to deliver the treatment. Linking the drug to albumin, which is carried in the blood, allows it to be delivered without solvents so that higher doses are tolerated.Tumors are effectively targeted due to their affinity for albumin.

Other clinical products being developed use nanotechnology to treat cancers, coronary restenosis and peripheral artery restenosis.

Acquired by Celegene

On June 30, 2010 Abraxis BioScience made an agreement to be acquired by the biotechnology company Celgene for $2.9 billion dollars at an implied price of $71.93 per share of Abrixis BioScience stock.

Timeline

June 30, 2010

Acquired by Celgene

On June 30, 2010 Abraxis BioScience made an agreement to be acquired by the biotechnology company Celgene for $2.9 billion dollars at an implied price of $71.93 per share of Abrixis BioScience stock.

2007

Abraxis BioScience was founded by Patrick Soon-Shiong.

People

Name
Role
LinkedIn

Aaron Kaufman

Employee

Ata Ghofrani

Employee

Bianca Anderson

Employee

Craig Lauer

Employee

Dave Adams

Employee

Jacki Petrovic

Employee

Joe Hogan

Employee

Lauren Weiniger

Employee

Paula Brunelle

Employee

Sanjay Gupta

Employee

Stephannie Perrin

Employee

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