Baylor College of Medicine

One hundred fifty years ago, Dmitri Mendeleev created the periodic table, a system for classifying atoms based on the properties of their nuclei. This week, a team of biologists studying the tree of life has unveiled a new classification system for cell nuclei and discovered a method for transmuting one type of cell nucleus into another.

Baylor researchers have discovered a pathway by which ER/HER2-positive breast tumors can transform into more aggressive, ER-negative-like subtypes--a discovery that could change the way breast cancer is tracked and treated, they believe. The key is the enzyme MAP kinase.

In the first and second phase of the trial, the Hyderabad-based vaccine maker studied the safety and immunogenicity of the vaccine candidate in about 360 participants in the age group of 18 to 65 years

The Phase III clinical study, which is to be conducted in 15 sites across India, will evaluate the Immunogenicity and Safety of Biological E's SARS-CoV-2 COVID-19 vaccine for protection against COVID-19 disease in about 1,268 healthy subjects in the age range of 18 to 80 years. It is intended to be part of a larger global Phase III study.

The phase III clinical study, to be conducted in 15 sites across India, will evaluate the immunogenicity and safety of Biological Es vaccine candidate in 1,268 healthy subjects

Biomedical scientists are increasingly using deconvolution methods, those used to computationally analyze the composition of complex mixtures of cells. One of their challenges is to select one method that is appropriate for their experimental conditions among nearly 50 available.

/PRNewswire/ -- The American College of Medical Genetics and Genomics (ACMG) welcomed five new directors, including a new president-elect, to its Board of...

People who suffer heart attacks frequently progress to chronic heart failure due to scarring and inflammation that hampers heart function. Researchers at Baylor College of Medicine showed that a small-molecule inhibitor of steroid receptor coactivators could prevent that progression in mice.

Baylor researchers showed that treatment with the probiotic L. reuteri or a metabolite of it restored normal social behavior in mouse models of a developmental brain disease similar to autism. They believe their findings could inspire new treatments for brain disorders that include behavioral components.

Immunai, a New York and Tel Aviv based biotech company, announced today $60M in funding, increasing the company's total funding-to-date to over $80M. Immunai integrates multi-omic single-cell analytics and machine learning to identify novel immunological insights that lead to the discovery and development of more effective and targeted immunotherapies. The Series A round was led by Schusterman Family Investments, Duquesne Family Office, Catalio Capital Management, and Dexcel Pharma, with...

/PRNewswire/ -- Tessa Therapeutics Ltd. (Tessa), a clinical-stage cell therapy company developing next-generation cancer treatments for hematological...

Research has shown that gut microbes can influence several aspects of the host's life, including aging. Given the complexity and heterogeneity of the human gut environment, elucidating how a specific microbial species contributes to longevity has been challenging. To explore the influence of bacterial products on the aging process, researchers at Baylor College of Medicine and Rice University developed a method that uses light to directly control gene expression and metabolite production from bacteria residing in the gut of the laboratory worm Caenorhabditis elegans.

/PRNewswire/ -- Baylor Scott & White Health, the largest not-for-profit health system in the state of Texas, announced plans to partner with Baylor College of...

Too much or too little iron in the body can lead to disease but organisms have developed ways to keep iron levels in balance. Ferroportin, the only known iron exporter that releases iron into the blood stream, is a crucial component of iron-balancing mechanisms.

Biological E. Limited, Dynavax Technologies Corporation, and Baylor College of Medicine announced that BE has initiated a Phase I/II clinical trial of its COVID-19 subunit vaccine candidate in India following approval from the Drugs Controller General of India.

/PRNewswire/ -- Biological E. Limited (BE), a Hyderabad-based vaccines and pharmaceutical company, Dynavax Technologies Corporation (NASDAQ: DVAX), a US-based...

Despite surpassing 1 million coronavirus cases, one thing was clear: Texas, like much of the nation, is overwhelmed by a virus that is more stubborn than the will of many quarantine-fatigued Americans who want to wish it away.

DURECT Corporation announced that Norman Sussman, MD, FAASLD, newly appointed Chief Medical Officer, will host a webinar on the treatment landscape and unmet medical need in treating patients with alcoholic hepatitis, as well as information on DURECT' investigational drug candidate, DUR-928, being developed for the treatment of AH.

Annexon Biosciences and AlloVir are seeking a $100 million IPO apiece in a buoyant market that shows no signs of slowing down.

Every week there are numerous scientific studies published. Here's a look at some of the more interesting ones.