Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Sònia Guedan Carrió0
Ramon Alemany Bonastre0
Manel Maria Cascallo Piqueras0
Date of Patent
October 29, 2024
0Patent Application Number
164052850
Date Filed
May 7, 2019
0Patent Citations
Patent Primary Examiner
Patent abstract
The invention is related to an oncolytic adenovirus that comprises a sequence encoding a hyaluronidase enzyme inserted in its genome. This adenovirus spreads more efficiently in the tumour mass and therefore the oncolytic effect is increased. Injecting the oncolytic adenovirus of the invention endovenously, tumour volume regressions are obtained. Therefore the oncolytic adenovirus of the present invention is useful for the treatment of a cancer or a pre-malignant state of cancer.
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