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Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Paul L. Hallenbeck0
Sandrina Phipps0
John Leonard Jakubczak0
Lori Clarke0
Mario Gorziglia0
Michael Kaleko0
Date of Patent
September 19, 2006
0Patent Application Number
100819610
Date Filed
February 22, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides novel viral vectors and methods useful for the minimization of leaky gene expression, and, in particular, of nonspecific transcriptional read-through of genes. Such constructs may be obtained by the insertion of an insulating sequence into a vector construct, such as for example a termination signal sequence upstream of the transcription initiation site of the respective transcription unit.
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