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US Patent 10239867 Modulators of ATP-binding cassette transporters

Patent 10239867 was granted and assigned to Vertex Pharmaceuticals on March, 2019 by the United States Patent and Trademark Office.

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Is a

Patent attributes

Patent Applicant

Vertex Pharmaceuticals

Current Assignee

Vertex Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Jason McCartney0

Mark T. Miller0

Mehdi Michel Jamel Numa0

Peter D. J. Grootenhuis0

Sara S. Hadida Ruah0

Xiaoqing Yang0

Jinglan Zhou0

Brian Bear0

...

Date of Patent

March 26, 2019

Patent Application Number

15659926

Date Filed

July 26, 2017

Patent Citations

US Patent 10071979 Process of producing cycloalkylcarboxamido-indole compounds

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US Patent 10022352 Modulators of ATP-binding cassette transporters

US Patent 10058546 Pharmaceutical compositions of (R)-1-(2,2-difluorobenzo[D][1,3]dioxo1-5-y1)-N-(1-(2,3-dihydroxypropy1)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-y1)-1H-indol-5-y1) cyclopropanecarbox-amide and administration thereof

0

US Patent 10081621 Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

0

Patent Citations Received

US Patent 12065432 Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid

0

US Patent 10738036 Deuterated CFTR modulators

US Patent 11564916 Pharmaceutical composition and administrations thereof

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US Patent 10906891 Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

US Patent 11578062 Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

US Patent 10975061 Modulators of ATP-binding cassette transporters

US Patent 10980746 Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases

US Patent 10987348 Modulators of ATP-binding cassette transporters

...

Patent Primary Examiner

Samantha L Shterengarts

Patent abstract

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

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