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US Patent 10022352 Modulators of ATP-binding cassette transporters

Patent 10022352 was granted and assigned to Vertex Pharmaceuticals on July, 2018 by the United States Patent and Trademark Office.

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Is a

Patent attributes

Patent Applicant

Vertex Pharmaceuticals

Current Assignee

Vertex Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Peter Diederik Jan Grootenhuis0

Jinglan Zhou0

Mark Thomas Miller0

Mehdi Michel Djamel Numa0

Sara Sabina Hadida Ruah0

Brian Richard Bear0

Fredrick F. Van Goor0

Jason McCartney0

Date of Patent

July 17, 2018

Patent Application Number

15078800

Date Filed

March 23, 2016

Patent Citations Received

US Patent 12065432 Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid

0

US Patent 11564916 Pharmaceutical composition and administrations thereof

0

US Patent 10906891 Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

US Patent 11578062 Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

US Patent 10975061 Modulators of ATP-binding cassette transporters

US Patent 10980746 Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases

US Patent 10987348 Modulators of ATP-binding cassette transporters

US Patent 11052075 Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid and administration thereof

0

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Patent Primary Examiner

Shawquia Jackson

Patent abstract

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

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