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US Patent 10975061 Modulators of ATP-binding cassette transporters

Patent 10975061 was granted and assigned to Vertex Pharmaceuticals on April, 2021 by the United States Patent and Trademark Office.

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Is a

Patent attributes

Patent Applicant

Vertex Pharmaceuticals

Current Assignee

Vertex Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

April 13, 2021

Patent Application Number

16276887

Date Filed

February 15, 2019

Patent Citations

US Patent 10076513 Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid and administration thereof

US Patent 10081621 Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

US Patent 10206877 Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases

US Patent 10231932 Process of preparing pharmaceutical compositions for the treatment of CFTR mediated diseases

US Patent 10239867 Modulators of ATP-binding cassette transporters

US Patent 10272046 Pharmaceutical composition and administrations thereof

US Patent 10302602 Process of conducting high throughput testing high performance liquid chromatography

US Patent 10537565 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

...

Patent Citations Received

US Patent 12065432 Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid

0

US Patent 11578062 Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

US Patent 11752106 Pharmaceutical composition and administrations thereof

US Patent 11951212 Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases

0

US Patent 11564916 Pharmaceutical composition and administrations thereof

US Patent 11639347 Modulators of ATP-binding cassette transporters

0

US Patent 11291662 Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

Patent Primary Examiner

Samantha L Shterengarts

Patent abstract

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

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