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US Patent 11639347 Modulators of ATP-binding cassette transporters

Patent 11639347 was granted and assigned to Vertex Pharmaceuticals on May, 2023 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Patent Applicant

Vertex Pharmaceuticals

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Current Assignee

Vertex Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Sara S. Hadida Ruah0

Xiaoqing Yang0

Brian Bear0

Fredrick Van Goor0

Jason McCartney0

Jinglan Zhou0

Mark T. Miller0

Mehdi Michel Jamel Numa0

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Date of Patent

May 2, 2023

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Patent Application Number

171819310

Date Filed

February 22, 2021

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Patent Citations

US Patent 10206877 Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases

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US Patent 10231932 Process of preparing pharmaceutical compositions for the treatment of CFTR mediated diseases

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US Patent 10239867 Modulators of ATP-binding cassette transporters

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US Patent 10272046 Pharmaceutical composition and administrations thereof

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US Patent 10302602 Process of conducting high throughput testing high performance liquid chromatography

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US Patent 10537565 Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

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US Patent 10597384 Solid forms of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid

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US Patent 10626111 Modulators of ATP-binding cassette transporters

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Patent Citations Received

US Patent 11951212 Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases

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Patent Primary Examiner

Samantha L Shterengarts

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Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

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