Flagship Pioneering

Flagship Pioneering

U.S-based venture capital firm funding U.S-startups in the life science industry.

Established in 2000, Flagship Pioneering (previously known as Flagship Ventures) is a venture capital firm founded by Noubar Afeyan and Edwin Kania. The firm primarily operates from Cambridge, Massachusetts although it also has an office in Ann Arbor, Michigan. The firm is currently managing a portfolio containing 37 companies and has sold off its shares in 121 companies. The firm’s most recent investment occurred in December 2018 for Indigo Agriculture, a biotechnology company specializing in plant microbiome agricultural services.

Funding

Flagship Pioneering focuses on funding startups that operate in the United States, especially in the Midwest region. The firm prefers to fund companies in the therapeutics, health technologies, life science, sustainability and clean technology business industries. It provides financing for companies at various stages of development, from incubation to growth stage. With its latest funding round raised in September 2017, the firm has managed to collect a total fund of $2.8 billion. During the September 2017 funding round, the firm amassed a total of $618 million in capital.

Timeline

May 27, 2020

Flagship Pioneering launches new agtech company to manage insect populations.

Funded Companies

Company
Description
Industry
Website
Location
Visterra

A company developing antibody-based biological medicines for kidney diseases and other chronic diseases. Visterra was acquired by Otsuka Pharmaceutical in 2018.

Biotechnology
Cambridge, Massachusetts
Codiak BioSciences

Codiak Biosciences is a biotechnology company developing exosome therapeutics.

Biotechnology
San Francisco
Editas Medicine

Editas Medicine is a genome editing company founded in 2013 that is using CRISPR technology to treat patients with genetically defined diseases.

Biotechnology
Colorado
Rubius Therapeutics

Rubius Therapeutics is a biotechnology company using stem cells to develop red blood cell cellular therapies.

Biotechnology
Cambridge, Massachusetts
T2 Biosystems

T2 Biosystems is a Lexington, Massachusetts-based company developing diagnostic products targeting sepsis and in vitro diagnostic products intended to target sepsis, hemostasis, bacteria, and lyme disease founded in 2006 by Robin Toft.

Healthcare
Lexington, Massachusetts
Indigo (company)

Indigo is an agricultural technology company utilizing natural microbiology and digital technologies to improve farmers' profitability, environmental sustainability and consumer health.

Artificial intelligence (AI)
Charlestown, Boston
Agios Pharmaceuticals

A public american pharmaceutical company

Biotechnology
Cambridge, Massachusetts
Avedro

Avedro is a Waltham, Massachusetts-based company.

Healthcare
Waltham, Massachusetts
Foghorn Therapeutics

Foghorn Therapeutics is a Cambridge, Massachusetts-based company developing therapies based on a system directing which genes cells express.

Biotechnology
Cambridge, Massachusetts
Syros Pharmaceuticals

A company focused on mapping and controlling the genes to treat diseases

Biotechnology
Watertown, Massachusetts
Intio

Intio is a Broomfield, Colorado-based diagnostic tools company focused on diagnostics for oncology.

Diagnostic tools
Broomfield, Colorado
Tangent Medical Technologies

Tangent Medical Technologies is an Ann Arbor, Michigan-based healthcare company.

Healthcare
Ann Arbor, Michigan
KSQ Therapeutics

KSQ Therapeutics is a Cambridge, Massachusetts-based company.

Cambridge, Massachusetts
Inari (company)

Agriculture
Boragen

Chemistry
Cygnal Therapeutics

Cygnal Therapeutics is a Cambridge, Massachusetts-based company.

Cambridge, Massachusetts
Evelo Biosciences

Company

Blend Therapeutics

Company

WikiCell Designs

19 Results
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Associated investment funds

Investment Fund
Total offering (USD)
Total sold (USD)
Location
Date signed
Flagship Pioneering Fund VI, L.P.
500,000,000
Cambridge, Massachusetts
September 14, 2017
Flagship Ventures Opportunities Fund I, L.P.
350,000,000
Cambridge, Massachusetts
June 29, 2016
Flagship Pioneering Special Opportunities Fund II, L.P.
700,000,000
Cambridge, Massachusetts
December 13, 2018
Flagship Ventures Fund IV, L.P.
250,000,000
Cambridge, Massachusetts
November 5, 2010
Flagship Ventures Fund V, L.P.
350,000,000
Cambridge, Massachusetts
December 17, 2014
5 Results
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People

Name
Role
LinkedIn

Adam J Koch

Employee

Avak Kahvejian

Employee

Bill Koteff

Employee

Brett Morrison

Employee

Brian Fiske

Employee

Bruce Miller

Investor

Chris Varma

Employee

Chuck Carelli

Chief Financial Officer

Chuck Eesley

Employee

David Berry

Employee

Deepak Jagannathan

Employee

Devesh Khanal

Employee

Edwin Kania

Co-Founder/Managing Partner

Emil Mamedov

Employee

Grace Brueckner

Employee

Harry Wilcox

Chief Operating Officer

Jacqueline Heard

Employee

Jaime Mateus

Employee

Jameson Rogers

Employee

Jason Patrick Schrum

Employee

Jernej Godec

Employee

Jerry Gupta

Employee

John Ballew

Employee

Kunle Demuren

Employee

Maneesh Gujrati

Employee

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Further reading

Title
Author
Link
Type
Date

Documentaries, videos and podcasts

Title
Date
Link

Companies

Company
CEO
Location
Products/Services

Agios

Alinea

Alvine Pharmaceutical

Avedro

Axcella

Bind Biosciences

News

Title
Author
Date
Publisher
Description
Amirah Al Idrus
July 16, 2020
FierceBiotech
It's back to biotech for Guillaume Pfefer, and not a moment too soon. Having spent four years at GlaxoSmithKline ushering its shingles vaccine through approval and onto the market, he's now taking on the dual role of CEO-partner at Flagship Pioneering, joining the biotech builder's team while taking the helm at one of its startups, Kintai Therapeutics.
BioSpace
July 7, 2020
BioSpace
Tessera Therapeutics emerges from three years of stealth operations to pioneer Gene WritingTM as a new genome engineering technology and category of genetic medicine
Rowan Walrath
June 3, 2020
AmericanInno
It's an interesting time to be a person on the move.
Srividya Kalyanaraman
May 27, 2020
AmericanInno
The startup wants to modulate insect health by supplying essential nutrients and vitamins lacking in the insect's diet.
Alex Keown
May 22, 2020
BioSpace
Pharma and life sciences companies bolster their executive leadership teams and boards with these Movers & Shakers.
BioSpace
March 12, 2020
BioSpace
Repertoire Immune Medicines harnesses our immune system's intrinsic ability to cure disease by decoding relevant Antigen-TCR codes and deploying them as breakthrough immune medicines in immuno-oncology, autoimmune disorders and infectious diseases
Jonathan Shieber
April 2, 2020
TechCrunch
Flagship Pioneering, the Boston-based biotech company incubator and holding company, said it has raised $1.1 billion for its Flagship Labs unit. Flagship, which raised $1 billion back in 2019 for growth stage investment vehicles, develops and operates startups that leverage biotechnology innovation to provide goods and services that improve human health and promote sustainable industries. [...]

References

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