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US Patent 7947646 Variant activin receptor polypeptides

Patent 7947646 was granted and assigned to Amgen on May, 2011 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
Amgen
Amgen
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7947646
Date of Patent
May 24, 2011
Patent Application Number
12074877
Date Filed
March 5, 2008
Patent Citations Received
‌
US Patent 11884715 Activin receptor type IIB variants and methods of use thereof
0
‌
US Patent 11685770 Stabilized receptor polypeptides and uses thereof
0
Patent Primary Examiner
‌
Robert Landsman
Patent abstract

The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.

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