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US Patent 11685770 Stabilized receptor polypeptides and uses thereof

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Is a
Patent
Patent
0

Patent attributes

Patent Applicant
Amgen
Amgen
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Current Assignee
Amgen
Amgen
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116857700
Date of Patent
June 27, 2023
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Patent Application Number
163885610
Date Filed
April 18, 2019
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Patent Citations
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US Patent 7736653 Pharmaceutical composition comprising an immunoglobulin Fc region as a carrier
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US Patent 7737260 Protein complex using an immunoglobulin fragment and method for the preparation thereof
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US Patent 7750127 Modified Fc molecules
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US Patent 7750128 Modified Fc molecules
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US Patent 7842663 Variants derived from ActRIIB and uses therefor
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US Patent 7947646 Variant activin receptor polypeptides
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US Patent 8067562 Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
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US Patent 8071538 Method of increasing muscle mass by administering a myostatin binding agent
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...
Patent Primary Examiner
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Gyan Chandra
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CPC Code
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C07K 14/71
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C07K 14/495
0

The present invention provides stabilized activin IIB receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the stabilized polypeptides and proteins. Compositions and methods for treating muscle-wasting diseases and metabolic disorders are also provided.

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