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US Patent 12092642 Systems and methods for biomolecule quantitation

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Contents

Is a
Patent
Patent
0

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
120926420
Patent Inventor Names
Jarrett D. Egertson0
Gregory Kapp0
Parag Mallick0
Date of Patent
September 17, 2024
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Patent Application Number
175795760
Date Filed
January 19, 2022
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Patent Citations
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US Patent 7855054 Multiplexed analyses of test samples
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US Patent 7964356 Method for generating aptamers with improved off-rates
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US Patent 8013134 Kit for proximity probing with multivalent proximity probes
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US Patent 8222047 Ultra-sensitive detection of molecules on single molecule arrays
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US Patent 8236574 Ultra-sensitive detection of molecules or particles using beads or other capture objects
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US Patent 8268554 Method for analyte detection using proximity probes
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US Patent 8404830 Method for generating aptamers with improved off-rates
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US Patent 8415171 Methods and systems for extending dynamic range in assays for the detection of molecules or particles
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...
Patent Primary Examiner
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Christopher M Gross
0
Patent abstract

Systems and methods for obtaining qualitative or quantitative measurements of proteoforms of polypeptides are described. The described methods include measurements of affinity reagent binding on single-molecule polypeptide arrays to distinguish between polypeptide isoforms. The described methods may provide high resolution quantitative comparisons of proteoforms with very low copy numbers.

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