US Patent 12064485 Disulfide bond stabilized polypeptide compositions and methods of use
Patent 12064485 was granted and assigned to Amicus Therapeutics on August, 2024 by the United States Patent and Trademark Office.
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US Patent 12064485 Disulfide bond stabilized polypeptide compositions and methods of use
Article
Patent abstract
Provided herein are polypeptides comprising one or more non-native cysteine residues that form a disulfide bridge between non-native cysteines within the protein or between non-native cysteines of two monomers of the protein. Such modified human polypeptides are useful in treatment of genetic diseases via enzyme replacement therapy and/or gene therapy.
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ce Feng Liu0
Hung Do0
Date of Patent
August 20, 2024
0Patent Application Number
173633330
Date Filed
June 30, 2021
0Patent Citations
Patent Primary Examiner
CPC Code
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