Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jonathan LeBowitz0
William S. Sly0
Stephen M. Beverley0
Date of Patent
July 23, 2013
0Patent Application Number
134812440
Date Filed
May 25, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
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