Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 31, 2010
Patent Application Number
11900659
Date Filed
September 12, 2007
Patent Citations Received
Patent Primary Examiner
Patent abstract
Targeted acid alpha-glucosidase therapeutics that localize to the lysosome are provided. The targeted therapeutics include a therapeutic agent, GAA, and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
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