US Patent 12063915 Humanized T cell co-receptor mice
Patent 12063915 was granted and assigned to Regeneron Pharmaceuticals on August, 2024 by the United States Patent and Trademark Office.
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US Patent 12063915 Humanized T cell co-receptor mice
Article
Patent abstract
The invention provides genetically modified non-human animals that express chimeric human/non-human T cell co-receptor polypeptides (e.g., CD4, CD8α, CD8β), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same.
Infobox
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Andrew J. Murphy0
Cagan Gurer0
Lynn Macdonald0
Naxin Tu0
Date of Patent
August 20, 2024
0Patent Application Number
170312550
Date Filed
September 24, 2020
0Patent Citations
Patent Primary Examiner
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