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US Patent 11981960 Spatial analysis utilizing degradable hydrogels

Patent 11981960 was granted and assigned to 10X Genomics on May, 2024 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
10X Genomics
10X Genomics
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Current Assignee
10X Genomics
10X Genomics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119819600
Patent Inventor Names
Jill Herschleb0
Bill Kengli Lin0
Cedric Uytingco0
Date of Patent
May 14, 2024
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Patent Application Number
173682590
Date Filed
July 6, 2021
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Patent Citations
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US Patent 6875572 Nucleic acid detection assays
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US Patent 6890741 Multiplexed detection of analytes
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US Patent 6897023 Method for determining relative abundance of nucleic acid sequences
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US Patent 6913881 Methods and compositions for detecting target sequences
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US Patent 6942968 Array compositions for improved signal detection
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US Patent 7011944 Invasive cleavage of nucleic acids
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US Patent 7057026 Labelled nucleotides
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US Patent 7083980 Tn5 transposase mutants and the use thereof
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...
Patent Citations Received
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US Patent 12129516 Quantitative and automated permeabilization performance evaluation for spatial transcriptomics
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US Patent 12060604 Spatial analysis of epigenetic modifications
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US Patent 12110541 Methods for preparing high-resolution spatial arrays
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US Patent 12117439 Compositions and methods for using fixed biological samples
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Patent Primary Examiner
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Samuel C Woolwine
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CPC Code
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C12Q 1/6837
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C12Q 1/6841
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Patent abstract

Provided are methods of capturing an analyte from a biological sample using a hydrogel that includes capture probes to capture the analyte, identifying a region of interest of the biological sample, and isolating the region of interest from the biological sample by removing a portion of the hydrogel that corresponds to the region of interest. Compositions and kits for performing the methods are also provided.

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