Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jeremy D. Metzler0
Mindy M. Steiniger-White0
William S. Reznikoff0
Date of Patent
August 1, 2006
0Patent Application Number
108265730
Date Filed
April 16, 2004
0Patent Citations Received
0
...
Patent Primary Examiner
Patent abstract
Tn5 transposase (Tnp) mutants that have higher transposase activities than the wild-type Tnp are disclosed. The Tn5 Tnp mutants differ from the wild-type Tnp at amino acid positions 54, 242, and 372 and have greater avidity than the wild-type Tnp for at least one of a wild-type Tn5 outside end sequence as defined by SEQ ID NO:3 and a modified Tn5 outside end sequence as defined by SEQ ID NO:5. Also disclosed are various systems and methods of using the Tnp mutants for in vitro or in vivo transposition.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
