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US Patent 12060604 Spatial analysis of epigenetic modifications

Patent 12060604 was granted and assigned to 10X Genomics on August, 2024 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Michael Schnall-Levin0

Christina Galonska0

Marlon Stoeckius0

Layla Katiraee0

Date of Patent

August 13, 2024

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Patent Application Number

183024210

Date Filed

April 18, 2023

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Patent Citations

US Patent 6875572 Nucleic acid detection assays

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US Patent 6890741 Multiplexed detection of analytes

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US Patent 6897023 Method for determining relative abundance of nucleic acid sequences

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US Patent 6913881 Methods and compositions for detecting target sequences

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US Patent 6942968 Array compositions for improved signal detection

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US Patent 7011944 Invasive cleavage of nucleic acids

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US Patent 7057026 Labelled nucleotides

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US Patent 7083980 Tn5 transposase mutants and the use thereof

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Patent Citations Received

US Patent 12129516 Quantitative and automated permeabilization performance evaluation for spatial transcriptomics

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Patent Primary Examiner

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Patent abstract

Provided herein are methods of identifying a methylation status of an analyte in a biological sample. Also provided herein are methods that combine identifying the methylation status with spatial technology to identify the location of a methylation status in a biological sample.

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