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US Patent 11964988 Fused heterocyclic compounds as RET kinase inhibitors

Patent 11964988 was granted and assigned to Array Biopharma Inc. on April, 2024 by the United States Patent and Trademark Office.

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Edits on 24 Apr, 2024
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 US Patent 11964988 Fused heterocyclic compounds as RET kinase inhibitors

Infobox
Is a
Patent
Patent
0
Patent Applicant
Array Biopharma Inc.
Array Biopharma Inc.
0
Current Assignee
Array Biopharma Inc.
Array Biopharma Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
119649880
Patent Inventor Names
Andrew T. Metcalf0
Brett Prigaro0
David A. Moreno0
Dean Kahn0
Donghua Dai0
Elizabeth A. McFaddin0
Gabrielle R. Kolakowski0
Ginelle A. Ramann0
Hailong Zhang0
James F. Blake0
Julia Haas0
Li Ren0
Megan L McKenney0
Shane M. Walls0
Yutong Jiang0
Date of Patent
April 23, 2024
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Patent Application Number
172749900
Date Filed
September 6, 2019
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Patent Citations
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US Patent 7384632 Agonist anti-trk-C monoclonal antibodies
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US Patent 7465726 Substituted pyrrolo[2.3-B]pyridines
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US Patent 7504509 Compounds and methods for development of Ret modulators
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US Patent 7514446 Pyrimidine compounds
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US Patent 7615383 Methods for treating neuropathy by agonist anti-trk-C monoclonal antibodies
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US Patent 7795273 Pyrazolo[1,5-a]pyridine-3-carboxylic acids as EphB and VEGFR2 kinase inhibitors
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US Patent 7863288 Compounds and methods for kinase modulation, and indications therefor
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US Patent 7863289 Compounds and methods for kinase modulation, and indications therefor
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US Patent 8026247 Bicyclic amides as kinase inhibitors
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US Patent 8067434 Compounds and methods for development of Ret modulators
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US Patent 8106069 Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors and pharmaceutical compositions comprising them
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US Patent 8114989 Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors
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US Patent 8129374 Method of using imidazolothiazole compounds for the treatment of disease
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US Patent 8198298 Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors
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US Patent 8299057 Substituted indazole derivatives active as kinase inhibitors
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US Patent 8338417 Compounds and compositions as c-kit and PDGFR kinase inhibitors
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US Patent 8354526 Pyrido [4, 3-D] pyrimidinone derivatives as kinase inhibitors
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US Patent 8399442 Pharmaceutical compounds
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US Patent 8450322 Substituted imidazo[1,2b]pyridazine compounds as Trk kinase inhibitors
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US Patent 8461161 Substituted pyrazines as inhibitors of kinase activity
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US Patent 8501756 Heterobicyclic carboxamides as inhibitors for kinases
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US Patent 8513263 Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors
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US Patent 8524709 Kinase inhibitor compounds
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US Patent 8552002 Compounds and compositions as protein kinase inhibitors
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US Patent 8568998 Methods of diagnosing, preventing and treating cancer metastasis
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US Patent 8629135 Pharmaceutical compositions comprising RET inhibitors and methods for the treatment of cancer
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US Patent 8637256 Immunoassay for determining the release of neurotensin into the circulation
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US Patent 8637516 Compounds and compositions as TRK inhibitors
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US Patent 8642035 Anti-TrkB antibodies
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US Patent 8673347 Polymer conjugates of K-252A and derivatives thereof
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US Patent 8686005 Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders
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US Patent 8691221 Analgesic treatment with prolonged effect
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US Patent 8741849 Kinase inhibitors and uses thereof
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US Patent 8754209 Indazole derivatives or pharmaceutically acceptable salts thereof as protein kinase inhibitors for proliferative diseases treatment, and a pharmaceutical composition containing the same as an active ingredient
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US Patent 8791123 Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors
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US Patent 8815901 Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors
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US Patent 8815906 Tyrosine kinase inhibitors
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US Patent 8895744 Alfa-carboline inhibitors of NPM-ALK, RET, and Bcr-Abl
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US Patent 8912194 CDK inhibitor for the treatment of mesothelioma
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US Patent 8912204 Compounds and methods for kinase modulation, and indications therefor
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US Patent 8933084 Macrocyclic compounds as Trk kinase inhibitors
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US Patent 8933230 Phosphorus-containing group-substituted quinoline, its preparation process, medical composition containing the compounds and application
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US Patent 8937071 Compounds as rearranged during transfection (RET) inhibitors
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US Patent 8946226 Use of CDK inhibitor for the treatment of glioma
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US Patent 9006256 Antitumor agent for thyroid cancer
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US Patent 9035063 Compounds as rearranged during transfection (RET) inhibitors
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US Patent 9102671 Compounds and compositions as TRK inhibitors
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US Patent 9149464 Bendamustine derivatives and methods of using same
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US Patent 9150517 Bendamustine derivatives and methods of using same
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US Patent 9186318 Quinolyl-containing hydroxamic acid compound and preparation method thereof, and pharmaceutical composition containing this compound and use thereof
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US Patent 9216172 Method for determining effectiveness of cancer treatment by assessing the presence of a KIF5B-RET chimeric gene
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US Patent 9242977 Trk-inhibiting compound
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US Patent 9260437 Compounds and methods for kinase modulation, and indications therefor
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US Patent 9273051 Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
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US Patent 9297011 KIF5B-RET fusion molecules and uses thereof
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US Patent 9321772 Substituted pyrazolo[3,4-D]pyrimidines and uses thereof
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US Patent 9487491 Diamino heterocyclic carboxamide compound
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US Patent 9493455 Azaindole derivatives as inhibitors of protein kinases
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US Patent 9505784 Fused 2-aminothiazole compounds
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US Patent 9522910 Protein kinase inhibitors (variants), use thereof in treating oncological diseases and a pharmaceutical composition based thereon
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US Patent 9550772 Azaindole derivatives as multi kinase inhibitors
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US Patent 9604980 Substituted pyrimidinyl and pyridinyl-pyrrolopyridinones, process for their preparation and their use as kinase inhibitors
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US Patent 9669028 Substituted 5-(pyrazin-2-yl)-1H-pyrazolo [3, 4-
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US Patent 9682083 Pyrrolo[2,3-D]pyrimidine derivatives, process for their preparation and their use as kinase inhibitors
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US Patent 9738660 Selective inhibitors for protein kinases and pharmaceutical composition and use thereof
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US Patent 9758508 2,3-dihydro-isoindole-1-on derivative as BTK kinase suppressant, and pharmaceutical composition including same
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US Patent 9789100 Compounds as rearranged during transfection (RET) inhibitors
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US Patent 9801880 Use of kinase inhibitors
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US Patent 10023570 Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors
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US Patent 10138243 Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
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US Patent 10174027 Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
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US Patent 10174028 Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors
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US Patent 6861509 Antibodies to Ret and RetL3
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Patent Primary Examiner
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Matthew P Coughlin
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CPC Code
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C07D 513/22
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C07D 498/22
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C07D 498/14
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C07D 487/14
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A61K 45/06
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A61K 31/55
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A61K 31/554
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A61K 31/519
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