Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Itsuro Shimada0
Akio Kamikawa0
Hiroshi Tomiyama0
Kazuhiko Iikubo0
Kazuo Kurosawa0
Takahiro Matsuya0
Yoshinori Iwai0
Yutaka Kondoh0
Date of Patent
November 8, 2016
0Patent Application Number
144729590
Date Filed
August 29, 2014
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided is a compound useful as an inhibitor against the kinase activity of EML4-ALK fusion protein. As a result of intensive and extensive studies on compounds having inhibitory activity against the kinase activity of EML4-ALK fusion protein, the present inventors found that the diamino heterocyclic carboxamide compounds of the present invention had inhibitory activity against the kinase activity of EML4-ALK fusion protein. By this finding, the present invention was completed. The compounds of the present invention can be used as a pharmaceutical composition for preventing and/or treating cancer, such as lung cancer, non-small cell lung cancer, and small cell lung cancer.
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