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US Patent 7615383 Methods for treating neuropathy by agonist anti-trk-C monoclonal antibodies

Patent 7615383 was granted and assigned to Genentech on November, 2009 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Current Assignee
Genentech
Genentech
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
76153830
Patent Inventor Names
Brigitte Devaux0
David L. Shelton0
Jo-Anne Hongo0
Leonard G. Presta0
Date of Patent
November 10, 2009
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Patent Application Number
115818650
Date Filed
October 16, 2006
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Patent Citations Received
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US Patent 11851434 Substituted pyrazolo[1,5-A]pyrazine compounds as ret kinase inhibitors
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US Patent 11998545 Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
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US Patent 11964988 Fused heterocyclic compounds as RET kinase inhibitors
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Patent Primary Examiner
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Christine J. Saoud
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Patent abstract

The invention concerns agonist anti-trkC monoclonal antibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention and/or treatment of cellular degeneration, including nerve cell damage associated with acute nervous cell system injury and chronic neurodegenerative diseases, including peripheral neuropathy.

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