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US Patent 11779632 IL-2 muteins and uses thereof

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 US Patent 11779632 IL-2 muteins and uses thereof

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Patent abstract

The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.

Infobox
Is a
Patent
Patent
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11779632
Patent Inventor Names
Erik Robert Sampson
Joanne L. Viney
Jyothsna Visweswaraiah
Kevin Lewis Otipoby
Nathan Higginson-Scott
Date of Patent
October 10, 2023
Patent Application Number
17201350
Date Filed
March 15, 2021
Patent Citations
‌
US Patent 7105653 IL-2 selective agonists and antagonists
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US Patent 9732134 Method of treating graft versus host disease using IL-2 muteins
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US Patent 9844582 Synergistic tumor treatment with extended-PK IL-2 and therapeutic agents
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US Patent 10035836 Modified IL-2 variants that selectively activate regulatory T cells
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US Patent 10086046 Agent for the treatment and or prophylaxis of an autoimmune disease and for the formation of regulatory T cells
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US Patent 10093711 Interleukin-2 muteins for the expansion of T-regulatory cells
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US Patent 10130659 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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US Patent 10138298 Anti-IL-2 antibodies and compositions and uses thereof
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US Patent 10150802 Superagonists, partial agonists and antagonists of interleukin-2
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US Patent 10166257 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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US Patent 10166273 Synergistic tumor treatment with antibodies targeting PD-1, PD-L1 or CTLA4 and integrin-binding-Fc-fusion protein
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US Patent 10174091 IL-2 muteins
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US Patent 10174092 IL-2 muteins
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US Patent 10183980 Superagonists and antagonists of interleukin-2
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US Patent 10184009 Mutant interleukin-2 polypeptides
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US Patent 10202464 Immunoconjugates
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US Patent 10227411 Modulation of T cells with bispecific antibodies and FC fusions
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US Patent 10227415 Methods of producing a zcytor17 heterodimeric cytokine receptor
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US Patent 10232053 Immunomodulatory oncolytic adenoviral vectors, and methods of production and use thereof for treatment of cancer
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US Patent 10251945 Anti-ICOS agonist antibodies and uses thereof
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US Patent 10260038 Protein modification of living cells using sortase
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US Patent 10272113 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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US Patent 10308696 IL2 and TNF immunoconjugates
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US Patent 10286113 Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto
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US Patent 10316104 Immunoconjugates
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US Patent 10293028 Use of low dose IL-2 for treating autoimmune related or inflammatory disorders
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US Patent 10293058 RNA containing composition for treatment of tumor diseases
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US Patent 10294287 Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases
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US Patent 10294305 Method for treating a GD2 positive cancer
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US Patent 10273489 Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier
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US Patent 10301384 Antibodies to IL-15
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US Patent 10323077 Expression of chimeric polypeptide with variable lymphocyte receptors on immune cells and uses for treating cancer
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US Patent 10323098 Mutant interleukin-2 polypeptides
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US Patent 10336801 Chemokine-cytokine fusion proteins of SDF-1 and CD40L
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US Patent 10350266 Method of treating cancer with a multiple integrin binding Fc fusion protein
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US Patent 10350304 Nucleic acid products and methods of administration thereof
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US Patent 10358477 IL-15Ralpha sushi domain—IL-15 fusion proteins
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US Patent 10363273 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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US Patent 10363321 Nucleic acid products and methods of administration thereof
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US Patent 10376564 Interleukin-2 for treating food allergy
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US Patent 10428145 PD-1 binding proteins and methods of use thereof
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US Patent 10493148 PD-1 agonist antibodies and uses thereof
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US Patent 10766958 Methods of treating vitiligo using PD-1 binding antibodies
Patent Primary Examiner
‌
Prema M Mertz
CPC Code
‌
A61K 38/2013

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