Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
March 6, 2007
Patent Application Number
10310719
Date Filed
December 4, 2002
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The invention provides cytokine fusion proteins with an increased therapeutic index, and methods to increase the therapeutic index of such fusion proteins. The fusion proteins of the invention are able to bind to more than one type of cytokine receptor expressed on cells and also bind to more than one cell type. In addition, the fusion proteins of the invention exhibit a longer circulating half-life in a patient's body than the corresponding naturally occurring cytokine.
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