Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kerry Louise Tyson0
Date of Patent
March 31, 2015
Patent Application Number
13583999
Date Filed
March 9, 2011
Patent Citations Received
Patent Primary Examiner
Patent abstract
A humanized agonistic antibody which binds human PD-1 comprising a heavy chain wherein the variable domain of the heavy chain comprises the sequence given in SEQ ID NO:1 for CDR-H1, the sequence given in SEQ ID NO: 2 for CDR-H2 and the sequence given in SEQ ID NO: 3 for CDR-H3 and the heavy chain framework region is derived from human sub-group sequence VH4 3-1 4-30.4+JH4 (SEQ ID NO: 33). The disclosure also extends to therapeutic uses of the antibody molecules, compositions and methods for producing said antibody molecules.
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