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US Patent 10983116 System, device and method for high-throughput multi-plexed detection

Patent 10983116 was granted and assigned to Yale University on April, 2021 by the United States Patent and Trademark Office.

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Contents

Patent abstractTimelineTable: Further ResourcesReferences
Is a
Patent
Patent

Patent attributes

Patent Applicant
Yale University
Yale University
Current Assignee
Yale University
Yale University
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
10983116
Patent Inventor Names
Jonathan Chen5
Rong Fan5
Yao Lu5
Date of Patent
April 20, 2021
Patent Application Number
16294853
Date Filed
March 6, 2019
Patent Citations
‌
US Patent 10274486 System, device and method for high-throughput multi-plexed detection
‌
US Patent 10584366 Analysis and screening of cell secretion profiles
Patent Citations Received
‌
US Patent 12105086 System, device and method for high-throughput multi-plexed detection
3
‌
US Patent 11893733 Treatment efficacy prediction systems and methods
4
Patent Primary Examiner
‌
Changhwa J Cheu
Patent abstract

The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.

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