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US Patent 10266495 Phenyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

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Is a

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

April 23, 2019

Patent Application Number

15977512

Date Filed

May 11, 2018

Patent Citations

US Patent 10005734 Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

Patent Citations Received

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US Patent 11498913 Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

US Patent 11376246 Inhibiting mutant IDH-1

US Patent 11963956 Inhibiting mutant isocitrate dehydrogenase 1 (mIDH-1)

0

US Patent 11497743 Treating patients harboring an isocitrate dehydrogenase 1 (IDH-1) mutation

US Patent 10532047 Solid forms of ((S)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile

US Patent 10550098 Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

US Patent 10577329 Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

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Patent Primary Examiner

D Margaret M Seaman

Patent abstract

The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula:

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